Library Screening TRIZ Cases
- Chip-Based Immunological Assay Without External Buffer
A biosensor chip uses the sample solution as a measurement solvent to detect antigen concentrations directly.
- Magnetic Micropallet Collection via Ferromagnetic Nanoparticles
Ferromagnetic nanoparticles embedded in photoresist allow magnetic probes to collect micropallets, bypassing slow inversion methods.
- Muscle-Derived Stem Cells for Personalized Drug Testing
Muscle-derived stem cells from micro-biopsies assess drug efficacy and adverse effects, reducing development costs.
- Cell-Based Microarrays for Rapid CTL-Antigen Detection
Segmented cell-based microarrays resolve low throughput bottlenecks by enabling parallel antigen identification via fluorogenic caspase activity.
- Patterned SAM Arrays via Polymer Stencil for Cell Screening
Polymer stencils define patterned self-assembled monolayer arrays, reducing manual handling steps while controlling ligand identity and density.
- Super-resolution imaging using multi-wavelength dye activation
Multi-wavelength illumination activates distinct fluorescent dye subsets to determine individual molecule positions with high spatial resolution.
- Micro-Radiobinding Assay for Low-Abundance Protein Screening
Segmented microarray immobilization determines binding affinity using 500-fold less target protein than classical filter-based assays.
- Three-Channel Fluorescence Scanner for FRET Correction
A three-channel fluorescence scanner measures sensitized emission to correct FRET distortion in two-color microarray experiments.
- Cell Microarray for High-Throughput Receptor Ligand Identification
A cell microarray system identifies receptor ligand interactions using fluorescent protein tags and magnetic separation techniques.
- Fluorescence-Based Screening of Pore-Forming Membrane Proteins
Fluorescence-based detection replaces slow growth assays to resolve minor differences in pore-forming properties with minute-range temporal resolution.
- Antibody Screening via VH-VL Domain Segmentation
Segment antibody variable domains to select stable pairs based on non-covalent interaction strength, overcoming slow traditional immunization methods.
- Residue Correlation Detection via Molecular Dynamics Simulation
Molecular dynamics simulations calculate residue metrics to identify correlated motions within biopolymer structures.
- SRM MRM Assay Peptide Selection for Cancer Protein Quantitation
Optimized peptide selection overcomes poor ionization and adherence issues to achieve accurate protein quantitation in cancer diagnostics.
- Antigen-Specific BCR Sequencing via Barcode and UMI Correction
Unique molecular identifiers correct amplification biases during multiplex sequencing, ensuring accurate pairing of heavy and light chains.
- Immortalized Mammalian Cell Panels for Drug Screening
Immortalized mammalian cell panels overcome limited primary cell lifespans to deliver reproducible in vitro models for compound toxicity assessment.