Microencapsulation Based TRIZ Cases
- Hyperbranched Polymer Nanoparticles for CRISPR Delivery
Hyperbranched poly-beta-amino ester polymers condense ribonucleoprotein complexes into nanoparticles.
- Ionizable Lipid Compounds for Nucleic Acid Delivery
Biodegradable tail chains in ionizable lipids resolve slow liver metabolism and toxicity trade-offs.
- Modified mRNA for Membrane Protein Expression
Modified mRNA molecules reduce genomic integration risks and immune responses while improving translation rates.
- Linear Double-Stranded Donor DNA for CRISPR Genome Editing
Short homology arms on linear donors resolve the trade-off between editing efficiency and precision, eliminating selection markers.