Modular bacterial libraries expand phage display diversity while limiting PCR mutations.
Amber-obligated phage libraries enable peptide selection with non-canonical amino acids for difficult ligand-binding targets.
Philo antibody libraries introduce mutations at VH CDR2 position 52 to expand epitope recognition capabilities.
Recombination vectors with cysteine-flanked random peptides enable rapid identification of biologically active sequences in bacterial cells.
Yeast surface display overcomes bacterial limitations by enabling eukaryotic post-translational modifications and precise affinity selection via FACS.