Nucleotide Libraries TRIZ Cases
- Microsatellite Length Measurement After Partial Mutagenesis
Partial mutagenesis disrupts repetitive regions before sequencing, helping measure microsatellite lengths despite amplification instability.
- DNA-Encoded Protein Display Through Ribosome Stalling
Ribosome stall sequences keep translated proteins attached to coding DNA for massively parallel display, sequencing, and functional screening.
- Full-Length Nucleic Acid Enrichment with Blocking Oligonucleotides
A blocking oligonucleotide protects full-length targets while 5′ exonuclease digests truncated strands for cloning-ready enrichment.
- Parallel Multiple Displacement Amplification With Lossless Barcoding
Parallel MDA uses staged primer roles and barcode adjustment to raise single-cell genome throughput while limiting amplification bias.
- Mediator-Assisted Reagent Transfer Between Droplets for Rate Control
Mediator molecules move reagents between droplet populations, adjusting concentration to control reaction rates.