Multiple protease digestions plus high-resolution mass spectrometry raise protein sequence coverage to distinguish proteoforms and modifications.
Protein measurement in uterine fluid replaces biopsy-based receptivity testing, enabling same-cycle embryo transfer planning with high accuracy.
Ceramide and phosphatidylcholine measurements improve cardiovascular risk stratification when LDL-C and HDL-C leave residual risk unresolved.
Urine biomarkers enable earlier feline CKD staging before clear clinical signs, while targeted nutrition helps slow disease progression.
Combining CRP, IL-6, PDGF-AB/BB, VEGF-A, and FTIR analysis improves early fracture-related infection diagnosis from blood samples.
Particles and labeled reference biomolecules improve biomarker quantitation, control enrichment quality, and reduce disease misclassification.
Fluorescently labeled immobilized peptides are sequenced one molecule at a time, enabling identification in complex mixtures.
Multi-marker OMICS ranking turns heterogeneous cell expression data into objective active agent scores and adjusted formulas.
b-Isox precipitation captures misfolded proteins from biofluids for cost-effective, non-invasive detection of prediabetes, diabetes, and cancers.
Affinity reagents target specific protein modifications to quantify proteoforms with high throughput and functional precision in biological samples.
Affinity-reagent arrays profile alpha-synuclein proteoforms at high throughput while preserving sensitivity and reproducibility for Parkinson's evaluation.
Individual proteins are immobilized and iteratively probed with affinity reagents to characterize and quantify diverse proteoforms at high sensitivity.