Non-negative matrix factorization resolves co-eluting compounds to enable accurate metabolite quantification without complex chromatography.
A hermetic sample holder uses a pivotally mounted cover to seal the cavity via pressure differentials.
Pulse labeling with stable isotopes tracks metabolic flux while maintaining homeostasis during sample preparation.
High-throughput mass spectrometry profiles chemically modified DNA and RNA nucleotides for disease diagnosis.
An automated method models and identifies defects in mass spectral peaks by generating and comparing sets of spectral data.
Dual-stage surface treatment stabilizes plasma by creating roughness with alumina particles then removing residue via dry ice sublimation.
Decomposing multiplexed product-ion spectra into single-component fragmentation patterns using extracted ion chromatogram peak shape detection.
Algorithmic cross-correlation resolves overlapping precursor and product ions, eliminating manual optimization bottlenecks.
A micrometer-scale ion trap fabricated on a monolithic gallium arsenide chip using semiconductor micro-electromechanical systems technology.
Monitoring load impedance detects second gas arrival, triggering high-frequency power supply when emission spectra fail to distinguish gases.
A document sampler uses mesh rollers to collect analytes directly from inserted papers.
Two-dimensional Kendrick mass defect plotting resolves ambiguity in degree-of-polymerization distribution when repeat units share similar compositions.
Switching ion polarity along the path isolates charging locations on ion optic devices, enabling precise cleaning to restore instrument sensitivity.
A nanopore mass spectrometry system sequences polymers by cleaving single molecules with a laser or electric field.
Resolves mass chromatogram shift errors from electronic drift and ion interactions by aligning signal intensity peaks for accurate component identification.