Peptide Sources TRIZ Cases
- Engineered synthase for production of tryptophan derivatives and intransigent substrates
Targeted beta-subunit mutations stabilize tryptophan synthase, enabling efficient production of analogs from challenging indole substrates.
- Peptidomimetics with Hydrogen Bond Surrogate Helices
A peptidomimetic structure uses hydrogen bond surrogates and beta amino acid residues to form stable helical conformations.
- Fibronectin-Targeting MRI Contrast Agent for Tumor Imaging
A fibronectin-targeting contrast agent enhances MR image contrast and relaxivity through specific peptide binding.
- AFP Peptide Segmentation for Breast Cancer Treatment
Segmenting the 8-amino acid EMTPVNPG core retains anti-estrotrophic activity while simplifying synthesis of lead compounds.
- Clamp Peptide Design for Zika Virus Detection
Segmented library evaluation reduces computational complexity while enabling rapid detection of Zika virus antigens.
- Continuous Osmotic Shock Apparatus for Periplasmic Protein Release
A continuous osmotic shock apparatus mixes high and low osmolality solutions to release periplasmic proteins from bacterial cells.
- Reversible Crosslinking Reagents for Protein Interaction Mapping
Novel reversible crosslinking reagents enable precise molecular mapping of protein interaction sites through efficient photochemical labeling.
- Diglycine Epitope Antibodies for Ubiquitin Site Profiling
Antibodies targeting diglycine remnants enable precise detection of ubiquitinated peptides after proteolytic cleavage.