Peptides TRIZ Cases
- Hybrid ELISA Lyme Disease Detection Using VlsE and C6 Antigens
A Hybrid ELISA combines recombinant VlsE protein and C6 peptide to improve early Lyme detection without sacrificing specificity.
- Cyclic Peptide Vehicles for Endosomal Escape and Cell Delivery
Low intracellular delivery from polymers and cationic liposomes is addressed with cyclic peptide vehicles that promote endosomal escape.
- Cyclic Peptide Compounds for Selective KRAS Inhibition
Specific residues and non-natural cyclic peptides target KRAS while minimizing interaction with HRAS and NRAS in RAS-mutant cancer cells.
- Macrocyclic Compounds for Blocking PD-L1/PD-1 and PD-L1/CD80 Interactions
PD-L1-binding macrocyclic compounds block PD-L1 interactions with PD-1 and CD80 to counter immune suppression and restore T-cell activation.
- Asymmetrically Branched Degradable PEG Derivative Limits Cell Vacuolation
An intracellularly cleavable oligopeptide helps a branched PEG derivative retain blood stability while preventing cell vacuolation.