Pharmaceutical Non-Active Ingredients TRIZ Cases

Segmenting peppermint oil into coated particles prevents volatility and dose dumping, ensuring reliable absorption during acute gastrointestinal flare-ups.

A capsule composite formulation containing separate independent parts of tadalafil and tamsulosin.

Specific amino acid and diol combinations in poly(ester urea)s resolve water solubility and complexation efficiency trade-offs.

Bicyclic peptide ligands merge dual cytotoxic payloads to resolve binding affinity limits in cancer therapy.

SGLT-2 inhibitors treat feline cardiomyopathies by improving cardiometabolic efficiency, reducing cardiac load, and increasing survival time.

Segmented polymer linkers enable high drug loading while maintaining aqueous solubility and preventing aggregation in antibody-drug conjugates.

Merging valsartan and sacubitril into a single fixed-dose composition overcomes limited efficacy from separate administration.

A medical device surface coating uses a labile linker to release bioactive agents from the substrate.

Crosslinked mRNA-polypeptide hybrids resolve throughput limits by enabling selection of vast libraries without individual sequence testing.

Segmented telodendrimers self-assemble into nanocarriers with hydrophobic cores to encapsulate chemotherapeutic agents.

A copolymer composition with carboxylic acids disperses quickly in water.

Alkoxymethyl side chains on polyether backbones block anti-PEG antibodies, reducing immunogenicity and allergic reactions in drug delivery.