Phosphorous Compound Active Ingredients TRIZ Cases
- HSP70 Inhibitor Compounds for Immunogenic Tumor Cell Death
Targeting HSP70 in tumor and mitochondrial compartments drives immunogenic cell death, boosts immune infiltration, and limits tumor growth.
- Linear ALK Inhibitors for LTK-Positive Multiple Myeloma
Linear ALK inhibitors extend treatment to ALK-negative, LTK-positive myeloma by triggering ER stress and apoptosis in hypersecretory cells.
- BTN3A1/BTN2A1 Binding Modulators for Stable Vγ9Vδ2 T Cell Activation
Small molecules bridge BTN3A1 and BTN2A1 to activate Vγ9Vδ2 T cells while improving plasma stability and drugability.