Powder Delivery TRIZ Cases
- Glu-Asp-Asp Peptide for Cartilage Matrix Regeneration
An EDD peptide promotes glycosaminoglycan and collagen production to address limited durability in surgical and cell-based cartilage repair.
- Silica Sol-Gel Vaults Protect Enzymes During Immobilization
Vault particles template silica sol-gel formation around proteins and enzymes, improving immobilization while limiting leakage and denaturation.
- Genomic Safe Harbors and Nanoparticles for Targeted Gene Therapy
Genomic safe harbors and engineered nanoparticles target gene addition in human stem cells while limiting insertional mutagenesis and immune responses.
- Mesoporous Sponge Spicules for 72-Hour Microchannel Drug Delivery
Solid microneedles leave skin micropores that close quickly; pre-loaded mesoporous sponge spicules keep channels open for at least 72 hours.
- Sheared Fibrin Particles for Protein-Preserving Wound Healing
High-density thermal polymerization can denature fibrin and inhibit cell migration; low-density sheared particles support wound healing and therapeutic-agent delivery.
- Biothiol-Activatable Nanoprobe for Glutathione Liver Imaging
A thiol-linked gold nanoparticle releases its reporter in liver-level glutathione, enabling detoxification imaging and enhanced clearance.
- Stable Tetrofosmin Radiopharmaceutical Composition Without Ascorbic Acid
Alternative radioprotectants replace UV-sensitive ascorbic acid to improve formulation stability and radiochemical purity.