Multifunctional dendritic nanoprobes integrate recognition elements to improve targeting specificity while reducing toxicity in healthy tissue.
L-phenylalanine conjugates cross the blood-brain barrier to deliver targeted radiation, reducing healthy tissue damage from residual tumor cells.
Octadentate chelators bind thorium-227 to prevent toxicity from unstable daughter isotopes.
A polypeptide molecular probe labeled with a radioactive nuclide enables noninvasive three-dimensional imaging of pancreatic islets.
Site-specific Fc modification via a linker reduces normal tissue accumulation and increases tumor concentration of radioactive antibodies.
Preliminary anti-action saturates normal tissue receptors with unlabeled compound, reducing background activity and improving tumor-to-background ratio.