Screening Process TRIZ Cases
- Base Editor Guide RNA Arrays for Targeted Plant Mutagenesis
Guide RNA arrays steer base editors to specific loci, enabling dense plant mutagenesis without double-strand breaks or major off-target effects.
- C9orf72 siRNA Composition for Selective CNS Gene Silencing
Chemically modified C9orf72 siRNA improves selective CNS gene silencing for ALS and FTD while addressing delivery and off-target constraints.
- CD33-Targeting siRNA Compositions for Neuroinflammation Control
Sequence-specific siRNA silences CD33 mRNA to lower Siglec3 levels and modulate neuroinflammation in CNS-targeted treatment.