Modified nucleosides curb innate immune activation, while PD-1/PD-L1 blockade strengthens antigen-specific responses for tumor targeting.
A coatable composition with biological salts forms a dried coating on microneedles that dissolves in interstitial fluids to release active agents.
Human TNFα antibodies restore efficacy in patients unresponsive to prior biologic therapies.
Modified 2-O-MLA adjuvants with specific buffers provide thermal stability and reduce reactogenicity.
An immunoconjugate delivers cytotoxic payloads directly to HER2-positive tumor cells via a targeted antibody linker system.
A pharmaceutical composition identifies compounds that induce immune tolerance by eliciting specific responses from responder and regulatory T-cells.