Sonopheresis TRIZ Cases
- Topical Lipolysis Composition for Non-Invasive Fat Reduction
A mixed-micelle topical composition improves skin penetration to reduce localized fat without surgery, injections, or prolonged recovery.
- Stem Cell-Nanoparticle Drug Complex for Stable Tumor Targeting
Stem cell-bound CNT or gold drug carriers improve tumor targeting and drug retention under blood and acidic pH conditions while limiting side effects.
- Ultrasound Sonoporation with Alternating MI for Gene Delivery
Alternating low and high ultrasound mechanical index boosts nucleic acid transfection, improves gene expression, and limits cellular damage.
- Alternating Electric Fields for Reversible Cancer Cell Permeabilization
Specific alternating electric field frequencies temporarily open cancer cell membranes, improving large-molecule delivery in glioblastoma treatment.
- NAD+ Peptide Iontophoresis for Sustained Regenerative Delivery
Anodal iontophoresis co-delivers NAD+ and therapeutic peptides through skin to extend regenerative effects with minimal irritation.
- Ultrasound-Triggered Chitosan Nanoparticles for Localized Tumor Drug Delivery
Non-bubble sonoporation uses ultrasound to open cell membranes locally, improving chitosan nanoparticle drug delivery while reducing normal-cell toxicity.
- Bi-Phasic Microbubble Clusters for Low-Power Ultrasound Drug Delivery
Bi-phasic microbubble and microdroplet clusters raise drug loading, resist washout, and enable lower-power ultrasound delivery with less vascular damage.
- Electroporation Delivery of Gelonin Across Cell Membranes
High-voltage electroporation opens temporary membrane pores so Gelonin can enter mammalian cells and achieve stronger targeted cytotoxicity.
- Light-Absorbing Submicron Particles for Follicular Skin Delivery
Submicron light-absorbing particles reach hair follicles by topical application and agitation, then use energy activation for targeted acne treatment.