2D-3D Medical Image Registration With Landmark-Based Initialization

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Solution Overview

Problem

Existing 2D-3D registration methods in robot-assisted surgery require a large number of iterations to converge, leading to time delays and potential failure, which hinders efficient image guidance.

Innovation Solution

The method initializes the computational configuration to align simulated and actual x-rays closely before starting iterations, improving convergence by reducing the number of required iterations and processing time.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If iterative methods are used for 2D-3D registration, then the registration accuracy is improved, but the processing time increases and convergence reliability deteriorates

Engineering Contradiction:
Improveregistration accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by initializing the iterative registration process with a pre-computed approximate transformation matrix derived from landmark point correspondence. This initial configuration brings the system close to the optimal solution before iterative refinement begins, thereby reducing the number of iterations needed and decreasing processing time while maintaining registration accuracy

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If iterative methods are used for 2D-3D registration, then the registration accuracy is improved, but the convergence reliability deteriorates

Engineering Contradiction:
Improveregistration accuracyVSAvoidconvergence reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

By performing preliminary initialization using landmark-based transformation estimation, the patent provides a reliable starting point that is anatomically and geometrically plausible. This reduces the risk of iterative methods diverging or converging to incorrect local minima, thereby improving convergence reliability while maintaining the ability to achieve high registration accuracy through subsequent iterative refinement

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If more iterations are performed, then the registration accuracy is improved, but the productivity decreases

Engineering Contradiction:
Improveregistration accuracyVSAvoidprocessing efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent performs a preliminary transformation estimation using readily available landmark point correspondences between 2D and 3D data sets. This initial configuration provides a close approximation of the correct registration state, allowing the iterative optimization to start from a near-optimal position and converge rapidly, thus achieving high accuracy without requiring numerous iterations and maintaining processing efficiency

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the parameter initialization strategy by using landmark-based geometric constraints to set initial transformation parameters before iterative optimization. This parameter initialization approach provides a physically meaningful starting point that reduces the search space for iterative algorithms, enabling faster convergence and improving productivity while maintaining registration accuracy

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS12484990B2Method and system for improving 2D-3D registration convergence
Publication Date: 2025.12.02 GLOBUS MEDICAL INC
  • US12484990B2 patent drawing
  • US12484990B2 patent drawing
  • US12484990B2 patent drawing

AI summary

A method for registration of digital medical images is provided. The method includes the step of storing a 3D digital medical image having a 3D anatomical feature and a first coordinate system and storing a 2D digital medical image having a 2D anatomical feature and a second coordinate system. The method further includes the steps of storing a placement of a digital medical object on the 3D digital medical image and the 2D digital medical image and generating a simulated 2D digital medical image from the 3D digital medical image, wherein the simulated 2D digital medical image comprises a simulated 2D anatomical feature corresponding to the 3D anatomical feature. The 2D anatomical feature is compared with the simulated 2D anatomical feature until a match is reached and a registration of the first coordinate system with the second coordinate system based on the match is determined.