2D Vessel Segmentation Orientation Detection for Reliable Angio-FFR

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Solution Overview

Problem

Inaccurate fluid dynamics assessments in vessel segmentation due to incorrect selection of starting and ending positions during vessel segmentation, leading to inverted blood flow direction and incorrect modeling results.

Innovation Solution

An apparatus and method for automatically detecting and verifying the vessel segmentation orientation using a trained classifier to determine the correct orientation of vessel segmentation, providing an indication to the user and potentially correcting the segmentation order.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual selection of starting and ending positions is used for vessel segmentation, then user control and flexibility are improved, but segmentation orientation errors increase leading to incorrect fluid dynamics assessments

Engineering Contradiction:
Improveuser controlVSAvoidsegmentation orientation accuracy
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The system performs fluid dynamics simulation in both proximal-to-distal and distal-to-proximal directions, then compares the results to determine which orientation produces physiologically plausible values. This feedback mechanism automatically detects and corrects segmentation orientation errors without requiring user intervention, thus maintaining ease of operation while significantly improving reliability.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system performs preliminary fluid dynamics simulations in both possible orientations before finalizing the assessment. By pre-calculating both proximal-to-distal and distal-to-proximal simulations and comparing results, the system proactively identifies orientation errors before they affect the final clinical decision, ensuring accurate assessments without adding significant user burden.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If automated classifier is used to detect vessel segmentation orientation, then segmentation orientation accuracy is improved, but device complexity increases

Engineering Contradiction:
Improveorientation detection accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system replaces complex manual orientation verification with an automated computational approach. Instead of requiring users to manually verify orientation or implement complex image analysis algorithms, the system uses fluid dynamics simulation as a virtual sensor to automatically detect orientation errors through physiological plausibility checks, substituting mechanical/visual verification with computational analysis.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system performs self-verification of segmentation orientation by automatically running simulations in both directions and comparing results. The fluid dynamics model serves as its own validation mechanism, eliminating the need for separate complex orientation detection algorithms or manual user verification, thus improving accuracy while keeping the system relatively simple.

Inventive Principle:
Principle #25Self-service

3Reliability

If fluid dynamics simulation is performed in both directions to verify orientation, then assessment reliability is improved, but computational time and resources increase

Engineering Contradiction:
Improvefluid dynamics assessment reliabilityVSAvoidcomputational time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system performs fluid dynamics simulations in both proximal-to-distal and distal-to-proximal directions, which is excessive action since only one orientation is ultimately correct. However, this redundancy is necessary to detect orientation errors. The system then uses the comparison results to identify the correct orientation, accepting the additional computational burden as a trade-off for ensuring assessment reliability in clinical applications.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentEP3871184B1Orientation detection for 2d vessel segmentation for angio-ffr
Publication Date: 2025.08.27 KONINKLIJKE PHILIPS NV
  • EP3871184B1 patent drawingFigure 1
  • EP3871184B1 patent drawingFigure 2
  • EP3871184B1 patent drawingFigure 3

AI summary

An apparatus for assessing a vessel of interest and a corresponding method are provided in which the modeling of the hemodynamic parameters using a fluid dynamics model can be verified by deriving feature values from the segmented vessel of interest and inputting these feature values into a classifier. The classifier may then determine, based on the feature values whether the segmentation has been performed from proximal to distal, from distal to proximal or cannot be determined from the provided data. An incorrect segmentation order can thus be identified and potentially be corrected, thereby avoiding inaccurate simulation results.