3D Functional-Anatomical Feature Matching Across Follow-Up Scans

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Solution Overview

Problem

Existing medical imaging technologies face challenges in accurately propagating marked functional or anatomical image features across follow-up scans taken at different times, due to significant changes in image features and patient positioning.

Innovation Solution

A computer-implemented method and system for follow-up local feature matching, which involves obtaining multiple functional and anatomical image data sets, generating 3D feature matching maps for functional and anatomical feature layers, calculating optimal matching coordinates, and outputting these coordinates for each image data set.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional image registration techniques are used to match features across follow-up scans, then the matching process can be performed, but the accuracy deteriorates due to significant changes in image features and patient positioning over time

Engineering Contradiction:
Improvefeature matching accuracyVSAvoidstudy duration
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent segments the image matching problem into multiple functional-anatomical feature layers (e.g., functional features like tracer uptake and anatomical features like tissue structure). Each layer is processed independently to generate separate matching maps, which are then integrated to produce the final matching result. This segmentation allows the system to handle different types of features that may change differently over time, improving overall matching accuracy despite significant temporal changes in the scans.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies local quality by generating separate 3D feature matching maps for different functional and anatomical feature types at local regions of interest. Instead of applying a uniform matching approach across the entire image, the system tailors the matching process to specific feature layers (e.g., lesion regions vs. surrounding tissue), allowing optimal matching strategies to be applied locally based on the specific characteristics of each feature type and region.

Inventive Principle:
Principle #3Local quality

2Ease of operation

If image alignment methods are applied to propagate features across scans, then feature propagation can be achieved, but distortions are introduced due to patient posture and positioning changes

Engineering Contradiction:
Improvefeature propagation capabilityVSAvoidimage alignment accuracy
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent extracts and removes the problematic image alignment step from the feature propagation process. Instead of aligning entire images (which introduces distortions due to patient positioning changes), the system directly propagates features by comparing local feature patterns across scans using the multi-layer matching approach. This extraction of the alignment step eliminates the source of distortion while preserving the ability to propagate features accurately.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces 3D feature matching maps as intermediary structures that facilitate feature propagation without requiring direct image alignment. These matching maps serve as mediators that capture the spatial relationships and feature correspondences between scans, allowing features to be propagated through the intermediary maps rather than through direct geometric transformation of the original images, thus avoiding alignment-induced distortions.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If conventional template matching is used for feature propagation, then the process can be completed, but reliability deteriorates when images are very different across follow-up scans

Engineering Contradiction:
Improveanalysis throughputVSAvoidfeature matching reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent transitions from conventional 2D template matching to 3D feature matching across multiple functional-anatomical layers. By adding the dimension of multiple feature layers (functional, anatomical, and their combinations) and utilizing 3D spatial information, the system creates a more robust matching space where features can be reliably identified even when individual 2D slices appear very different. This dimensional expansion provides additional constraints and information that improve reliability without sacrificing throughput.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentUS12347108B2System and method for follow-up local feature matching based on multiple functional-anatomical feature layers
Publication Date: 2025.07.01 GE PRECISION HEALTHCARE LLC
  • US12347108B2 patent drawing
  • US12347108B2 patent drawing
  • US12347108B2 patent drawing

AI summary

A method includes obtaining functional and anatomical image data sets from a subject acquired at different dates. The method includes receiving a volumetric coordinate of interest in a specified functional and anatomical image data set. The method includes generating a 3D feature matching map for at least one functional feature layer type and for at least one anatomical feature layer type for each non-specified functional and anatomical image data set relative to the specified functional and anatomical image data set utilizing the volumetric coordinate of interest. The method includes generating a best matching coordinate and a corresponding confidence metric value for each 3D feature matching map. The method includes calculating an optimal matching coordinate to the volumetric coordinate of interest based on the best matching coordinates and their corresponding confidence metric values and outputting a respective optimal matching coordinate for each of the non-specified functional and anatomical image data sets.