3D Interdigital Micro-mixers for Rapid Viscosity Mixing

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Solution Overview

Problem

Current micro-fluid processing technologies face challenges in efficiently mixing reactants with different viscosities and immiscible liquids, as well as controlling the incremental introduction of limiting reagents, particularly due to high processing times and costs associated with handling large volumes of reagents in planar micro-fluid devices.

Innovation Solution

The development of interdigital micro-mixers and micro-reactors with micro-channels that utilize thin fluid laminae and low aspect ratios to achieve rapid mixing, combined with advanced fabrication techniques such as diffusion bonding and embossing, allowing for high-throughput and cost-effective production of devices capable of mixing reactants with different viscosities and immiscible liquids, and controlled incremental introduction of reagents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If planar micro-fluid devices are used for mixing reactants, then device simplicity is maintained, but processing time increases and workspace requirements become very large

Engineering Contradiction:
Improvedevice structureVSAvoidprocessing time
Core Design Contradiction:
Device complexityVSLoss of time

Solution Approach 1:

The patent transitions from planar (2D) micro-fluid devices to three-dimensional (3D) micro-fluid devices with vertical stacking of micro-channels. This dimensional change allows reactants to be mixed in multiple layers simultaneously, dramatically reducing processing time and workspace requirements while maintaining device functionality.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The patent divides the mixing process into multiple independent micro-channels that can operate in parallel. Each micro-channel handles specific reactant mixing tasks, allowing simultaneous processing of multiple reactions, thereby reducing overall processing time and workspace requirements.

Inventive Principle:
Principle #1Segmentation

2Device complexity

If planar micro-fluid devices are used for handling large volumes of reagents, then single-layer simplicity is maintained, but workspace requirements and processing difficulty increase

Engineering Contradiction:
Improvedevice structureVSAvoidworkspace requirements
Core Design Contradiction:
Device complexityVSArea of stationary object

Solution Approach 1:

The patent utilizes vertical stacking of multiple micro-channel layers to handle large volumes of reagents. Instead of expanding horizontally in a planar configuration, the device expands vertically, reducing the workspace footprint while maintaining the capacity to handle large reagent volumes through multi-layer parallel processing.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The patent implements nested micro-channels where smaller channels are positioned within or alongside larger channels in a vertical stack. This nesting allows efficient use of space, enabling the device to handle large volumes of reagents through multiple concentric or adjacent flow paths without proportionally increasing workspace requirements.

Inventive Principle:
Principle #7Nested doll (Nesting)

3Ease of manufacture

If conventional molding and lithography techniques are used to construct micro-fluid devices, then manufacturing simplicity is maintained, but manufacturing cost increases for high-throughput applications

Engineering Contradiction:
Improvemanufacturing processVSAvoidmanufacturing cost
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent divides the micro-fluid device into multiple separable layers that can be manufactured independently using conventional molding and lithography techniques. Each layer can be produced separately and then assembled, allowing for parallel manufacturing of multiple components, which reduces overall manufacturing cost for high-throughput applications while maintaining manufacturing simplicity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent combines multiple micro-channel layers into a single integrated 3D device structure. By merging independently manufactured layers through stacking and bonding, the device achieves high throughput capability while utilizing cost-effective conventional manufacturing techniques for each individual layer, rather than requiring expensive custom high-throughput manufacturing processes.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS9421507B2Micro-channels, micro-mixers and micro-reactors
Publication Date: 2016.08.23 THE STATE OF OREGON ACTING BY & THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIV
  • US9421507B2 patent drawing
  • US9421507B2 patent drawing
  • US9421507B2 patent drawing

AI summary

A fluid micro-mixer apparatus includes a plurality of first microchannels for receiving a first fluid and a plurality of second microchannels for receiving a second fluid. A mixing chamber flow path is disposed to receive the first and second fluids after the first and second fluids exit their respective output ports. The mixing chamber flow path can include a first mixing chamber in the vicinity of the respective output ports, and the mixing chamber flow path can separate into at least two different flow paths downstream from the first mixing chamber.