3D Microfluidic Channel Fabrication Using Multi-Focus Ultrafast Lasers

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Solution Overview

Problem

Current methods for processing micro-fluidic chips are limited to two-dimensional channels and require high laser energy or repeated scanning, making it inefficient for fabricating complex three-dimensional micro-channels.

Innovation Solution

The use of multi-focus ultrafast laser technology, specifically converting femtosecond laser into an array-type multi-focus femtosecond laser for fractional ablation, followed by secondary ablation with picosecond or femtosecond ultra-short pulse laser, and ultrasonic-assisted hydrofluoric acid etching to efficiently process micro-channels on micro-fluidic chips.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a tightly-focused single femtosecond laser beam is used for ablation, then processing precision is improved, but processing efficiency deteriorates due to low ablation rate requiring repeated scanning

Engineering Contradiction:
Improveablation precisionVSAvoidprocessing efficiency
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The invention divides a single high-energy laser beam into multiple lower-energy beams using beam splitting optics. These multiple beams are then focused simultaneously at different positions within the material to create multiple focal points, enabling parallel ablation of multiple channels or features in a single scan pass, thereby dramatically improving processing efficiency while maintaining precision through controlled focal positioning

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention transitions from single-point sequential ablation to multi-point parallel ablation by introducing spatial distribution of multiple focal points along the laser propagation direction and transverse plane. This dimensional expansion allows simultaneous processing of multiple locations, converting a one-dimensional sequential process into a three-dimensional parallel process that enhances throughput

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Volume of moving object

If high laser energy is used to achieve desired structural size in ablation, then ablation depth and width are improved, but thermal effect on surrounding material increases

Engineering Contradiction:
Improveablation volumeVSAvoidthermal effect
Core Design Contradiction:
Volume of moving objectVSObject-affected harmful factors

Solution Approach 1:

The total laser energy required for ablation is segmented into multiple lower-energy beams distributed across multiple focal points. Each individual beam carries reduced energy that minimizes thermal diffusion to surrounding material, while the cumulative effect of multiple beams achieves the desired total ablation volume through spatial distribution rather than concentration of energy

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention applies different energy levels to different spatial locations by distributing laser energy across multiple focal points. Each local region receives appropriate energy for precise ablation without excessive thermal accumulation, while the overall structure achieves the required dimensions through the collective contribution of multiple localized ablation zones

Inventive Principle:
Principle #3Local quality

3Manufacturing precision

If repeated scanning is performed to fabricate micro-fluidic channels, then desired structural size is achieved, but processing time increases

Engineering Contradiction:
Improvechannel dimensionsVSAvoidprocessing time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The processing task is segmented into multiple simultaneous ablation operations performed by multiple laser beams acting in parallel. Instead of sequentially scanning the same path multiple times to build up channel dimensions, multiple beams create multiple channels or features simultaneously in a single pass, reducing the number of scanning cycles required while maintaining dimensional accuracy through precise focal control

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention maintains continuous useful action by having multiple laser beams operate simultaneously throughout the processing field, eliminating idle time between sequential scans. All beams perform productive ablation work concurrently during each scan pass, maximizing the utilization of laser energy and minimizing non-productive scanning cycles

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enhances processing precision, efficiency, and safety, allowing for large-scale, flexible, and high-precision fabrication of complex three-dimensional micro-channels on micro-fluidic chips with reduced energy consumption.

Implementation Method 1

converting femtosecond laser into an array-type multi-focus femtosecond laser using a laser multi-focus technology to perform fractional ablation on a section of micro-channels to be processed of the micro-fluidic chip

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 2

the array-type multi-focus femtosecond laser is output by using laser multi-focus technology to efficiently process micro-fluidic chips

Methodology Applied
Scientific EffectMulti-focus ablation: Laser Ablation

Implementation Method 3

performing a secondary ablation on the micro-channels to be processed of the micro-fluidic chip using a picosecond or a femtosecond ultra-short pulse laser

Methodology Applied
Scientific EffectUltra-short pulse laser ablation: Laser Ablation

Implementation Method 4

subjecting the micro-fluidic chip to ultrasonic-assisted hydrofluoric acid etching to dredge the micro-channels after undergoing the fractional ablation and the secondary ablation

Methodology Applied
Scientific EffectUltrasonic vibration: Ultrasonic Vibration

Data Source

PatentUS12090576B2Device and method for processing micro-channel on microfluidic chip using multi-focus ultrafast laser
Publication Date: 2024.09.17 SHANGHAI LANGYAN OPTOELECTRONICS TECH CO LTD
  • US12090576B2 patent drawing
  • US12090576B2 patent drawing
  • US12090576B2 patent drawing

AI summary

A method for processing a micro-channel of a micro-fluidic chip using multi-focus ultrafast laser, in which an array-type multi-focus femtosecond laser is used to perform fractional ablation on the micro-fluidic chip, and then pulse laser is used to perform secondary ablation on the micro-fluidic chip. Ultrasonic-assisted hydrofluoric acid etching is performed on the micro-fluidic chip after ablation to obtain a true three-dimensional micro-channel on the micro-fluidic chip. A device for processing a micro-channel of a micro-fluidic chip using multi-focus ultrafast laser is also provided.