3D Printed Ferroelectric Artificial Artery for Real-Time Pressure Sensing

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Solution Overview

Problem

Current vascular grafts fail to effectively monitor local physiological signals in real-time, leading to delayed detection of complications such as stenosis and occlusions, which often require complex and risky surgical procedures.

Innovation Solution

3D printed artificial blood vessels using ferroelectric materials with piezoelectric responses, specifically a composite of ferroelectric potassium sodium niobate (KNN) particles embedded in a polyvinylidene fluoride (PVDF) polymer matrix, allowing for real-time pressure and motion sensing through electric field-assisted additive manufacturing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional casting, molding or electrospinning technology is used to fabricate ferroelectric structures, then manufacturing complexity is reduced, but manufacturing precision and anatomical matching are insufficient

Engineering Contradiction:
Improveanatomical matching precisionVSAvoidmanufacturing process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent uses electric field assisted 3D printing to change the manufacturing parameters, allowing precise control of the ferroelectric structure geometry to match patient-specific anatomy while maintaining manufacturing feasibility through automated digital modeling and printing processes

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces conventional mechanical manufacturing methods (casting, molding, electrospinning) with electric field assisted 3D printing, where an electric field is applied during the printing process to induce piezoelectric properties in the printed structure, achieving both anatomical precision and functional performance

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If 3D printed ferroelectric materials are poled using conventional methods, then piezoelectric properties are achieved, but poling time is excessively long

Engineering Contradiction:
Improvepiezoelectric performanceVSAvoidpoling time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies the poling electric field during the 3D printing process itself, before the material fully solidifies, so that the piezoelectric domains are aligned while the material is still in a more compliant state, eliminating the need for a separate, time-consuming post-printing poling step

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent merges the 3D printing process with the poling process into a single integrated operation, where the electric field is applied simultaneously with material deposition, combining two previously separate steps into one efficient process

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If high electric field is applied to pole 3D printed ferroelectric materials, then piezoelectricity is improved, but manufacturing reliability decreases due to high conductivity and low breakdown strength

Engineering Contradiction:
Improvepiezoelectric responseVSAvoidmanufacturing reliability
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent applies the poling electric field during the printing process when the material is still in a semi-molten or compliant state, before full crystallization and hardening occur, allowing domain alignment at lower electric field intensities that do not exceed the breakdown strength of the printed structure

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the temporal parameter of material state during poling, applying the electric field at an optimal moment when the material properties (conductivity, breakdown strength, domain mobility) are most favorable for successful poling without damage

Inventive Principle:
Principle #35Parameter changes

4Ease of manufacture

If high printing temperatures are used for 3D printing, then material extrusion is achieved, but ferroelectric phase is lost due to low Curie temperature

Engineering Contradiction:
ImproveprintabilityVSAvoidferroelectric phase stability
Core Design Contradiction:
Ease of manufactureVSStability of the object's composition

Solution Approach 1:

The patent applies the poling electric field during the printing process at elevated temperatures, inducing piezoelectric domain alignment while the material is in a high-temperature compliant state, and then rapidly cooling the printed structure to lock in the ferroelectric phase below the Curie temperature

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent exploits the phase transition behavior of ferroelectric materials near their Curie temperature, applying the poling field during the transition when domain mobility is highest, then rapidly cooling through the transition to stabilize the ferroelectric phase with aligned domains

Inventive Principle:
Principle #36Phase transitions

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables early detection of hemodynamically significant lesions and vessel failures with high fidelity and durability, reducing morbidity and mortality by providing a self-powered, biocompatible, and flexible sensing capability within the body.

Implementation Method 1

Ferroelectric materials are an ideal selection for precision pressure and motion sensing owing to their outstanding piezoelectric responses

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Implementation Method 2

Electric field assisted additive 3D printing is a promising method to quickly produce complex piezoelectric structures

Methodology Applied
Scientific EffectElectric field poling: Electric Field

Data Source

PatentUS11849642B23D printed and in-situ poled flexible piezoelectric pressure sensor
Publication Date: 2023.12.19 WISCONSIN ALUMNI RES FOUND
  • US11849642B2 patent drawing
  • US11849642B2 patent drawing

AI summary

A piezoelectric artificial artery can be 3D printed to provide the real-time precise sensing of blood pressure and vessel motion patterns enabling early detection of partial occlusions. An electric-field assisted 3D printing method allows for rapid printing and simultaneously poled complex ferroelectric structures with high fidelity and good piezoelectric performance. The print material consists of ferroelectric potassium sodium niobate (KNN) particles embedded within a ferroelectric polyvinylidene fluoride (PVDF) polymer matrix.