3D Tissue Layer Segmentation with Motion-Corrected Feature Alignment

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Solution Overview

Problem

Current medical imaging technologies, such as OCT, suffer from poor accuracy in layer segmentation due to the continuity of layer distribution in three-dimensional space, leading to limited diagnostic information and utilization of medical images.

Innovation Solution

A method and apparatus for performing layer segmentation on a tissue structure in a medical image using feature extraction, alignment, and segmentation networks to obtain three-dimensional layer distribution, which includes determining offsets and performing feature alignment on image features to correct for tissue movement during scanning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If two-dimensional layer segmentation is performed on each OCT image independently, then the processing complexity is reduced, but the segmentation accuracy deteriorates due to loss of three-dimensional continuity information

Engineering Contradiction:
Improveprocessing complexityVSAvoidsegmentation accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent transitions from two-dimensional independent segmentation to three-dimensional segmentation by incorporating the continuity of layer distribution across multiple OCT images. The system processes a stack of two-dimensional OCT images together, utilizing the third dimension (depth/scan direction) to maintain layer continuity information, thereby improving segmentation accuracy while managing processing complexity through efficient 3D convolution operations.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Productivity

If three-dimensional segmentation is performed directly without feature alignment, then the processing speed is improved, but the segmentation accuracy deteriorates due to tissue movement during scanning

Engineering Contradiction:
Improveprocessing speedVSAvoidsegmentation accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent applies feature alignment as a preliminary step before three-dimensional segmentation. By aligning the image features of multiple OCT images based on detected offsets (caused by tissue movement during scanning), the system corrects misalignments in advance. This preliminary alignment action ensures that subsequent 3D segmentation operates on corrected data, improving accuracy without significantly impacting processing speed.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If feature alignment is performed to correct tissue movement, then the segmentation accuracy is improved, but the processing time increases

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent divides the processing into distinct segmentation steps: first detecting offsets between images, then aligning features based on these offsets, and finally performing three-dimensional segmentation. This segmented approach allows the system to apply alignment only where necessary (based on detected offsets) rather than processing all images uniformly, thereby reducing overall processing time while maintaining accuracy improvements from alignment.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS12400332B2Method and apparatus for performing layer segmentation on tissue structure in medical image, device, and medium
Publication Date: 2025.08.26 TENCENT TECHNOLOGY (SHENZHEN) CO LTD
  • US12400332B2 patent drawing
  • US12400332B2 patent drawing
  • US12400332B2 patent drawing

AI summary

A computer device performs feature extraction on two-dimensional medical images included in a three-dimensional medical image, to obtain image features corresponding to the two-dimensional medical images. The three-dimensional medical image are obtained by continuously scanning a target tissue structure. The computer device determines offsets of the two-dimensional medical images in a target direction based on the image features. The computer device performs feature alignment on the image features based on the offsets, to obtain aligned image features. The computer device performs three-dimensional segmentation on the three-dimensional medical image based on the aligned image features, to obtain three-dimensional layer distribution of the target tissue structure in the three-dimensional medical image.