3D Medical Volume GAN Training With Multi-Plane Discriminator Feedback

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Solution Overview

Problem

The challenge in utilizing deep learning for medical image analysis is the difficulty in acquiring large amounts of training data due to high costs and privacy concerns, and the issue of maintaining consistency when reconstructing medical image data from 3D to 3D space, leading to distortion.

Innovation Solution

A method and apparatus for training a medical volume data generative model using a generator network and multiple discriminator networks to generate and discriminate 2D images from different angles, updating the generator network based on discrimination results to ensure consistency and accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a single discriminator network is used to train the generator network, then the training process is simple, but the generated 3D medical volume data lacks consistency and exhibits distortion

Engineering Contradiction:
Improveconsistency of 3D medical volume dataVSAvoidnumber of discriminator networks
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The single discriminator network is segmented into multiple discriminator networks, each responsible for evaluating 2D images from specific viewing angles (axial, coronal, sagittal planes). This segmentation allows each discriminator to specialize in detecting distortions from particular perspectives, collectively ensuring comprehensive 3D consistency without requiring excessive complexity in any single component.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The approach transitions from evaluating 3D volume data directly to evaluating 2D cross-sectional images at multiple angular dimensions. By projecting the 3D synthetic volume data into 2D slices across different anatomical planes and having discriminators evaluate these 2D representations, the system captures consistency requirements from multiple spatial dimensions, thereby ensuring overall 3D consistency.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If multiple discriminator networks are used to ensure 3D consistency, then the quality of generated data improves, but the training complexity and computational cost increase

Engineering Contradiction:
Improvequality of generated medical volume dataVSAvoidtraining system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Each discriminator network is designed with multi-functionality, evaluating 2D images not only for authenticity (real vs. synthetic) but also for consistency with the synthetic 3D volume data from which they were projected. This universal evaluation approach allows the discriminators to simultaneously assess multiple quality aspects, reducing the need for separate specialized networks and managing training complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The multiple discriminator networks provide comprehensive feedback to the generator network by evaluating synthetic 2D images from various viewing angles and comparing them against real 2D images. This multi-perspective feedback mechanism guides the generator to produce 3D volume data that maintains consistency across all anatomical planes, improving reliability through iterative refinement while managing training complexity through structured feedback loops.

Inventive Principle:
Principle #23Feedback

3Productivity

If 3D medical volume data is generated without multi-angle validation, then the training process is faster, but distortion occurs in the reconstructed 3D space

Engineering Contradiction:
Improvetraining speedVSAvoiddistortion-free 3D reconstruction
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The system performs preliminary validation by projecting the generated 3D synthetic volume data into 2D images across multiple anatomical planes (axial, coronal, sagittal) before final evaluation. This preliminary multi-angle projection ensures that consistency requirements are established early in the training process, preventing distortion from developing in the 3D reconstruction while maintaining efficient training through pre-organized evaluation structures.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12608846B2Method and apparatus for training generative model for 3D consistent medical volume data
Publication Date: 2026.04.21 GENGENAI INC
  • US12608846B2 patent drawing
  • US12608846B2 patent drawing
  • US12608846B2 patent drawing

AI summary

A method for training a 3D space consistent medical volume data generative model is provided, which is performed by one or more processors and which includes generating a synthetic volume data using a generator network, receiving real volume data, generating a plurality of 2D images based on the synthetic volume data and the real volume data, discriminating whether each of the plurality of generated 2D images is real or fake by using a plurality of discriminator networks, and updating the generator network based on discrimination results of the plurality of discriminator networks.