3D/4D CEUS Imaging Parameter Control for Real-Time Perfusion Capture

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Solution Overview

Problem

Existing 2D real-time CEUS imaging frame rates are insufficient for capturing the complete perfusion process of microbubbles, limiting the ability of doctors to provide reliable diagnostic results due to low imaging velocities and limited computing power of current systems.

Innovation Solution

A 3D/4D CEUS imaging apparatus and method that allows for selectable contrast imaging modes and velocities, adjusting parameters such as number of transmissions, line density, and region of interest (ROI) to enhance imaging speed and data processing capacity, particularly using planar array probes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If 3D/4D contrast-enhanced imaging is performed with high imaging velocity to capture complete perfusion process, then diagnostic reliability is improved, but data processing load increases beyond current system computing power

Engineering Contradiction:
Improvediagnostic reliabilityVSAvoiddata processing load
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the imaging process into multiple phases (pre-contrast, arterial phase, venous phase, delayed phase) and acquires data selectively in each phase. This segmentation allows the system to capture complete perfusion processes at high velocities without overwhelming the computing system, as only relevant phase data is processed and stored for diagnostic analysis

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system performs preliminary actions by pre-configuring imaging parameters, selecting regions of interest (ROIs), and preparing processing algorithms before the actual contrast enhancement occurs. This preliminary preparation enables the system to rapidly process high-velocity imaging data during the actual perfusion capture without exceeding computing power limits

Inventive Principle:
Principle #10Preliminary action

2Speed

If imaging velocity is increased to meet real-time observation requirements, then observation capability is improved, but imaging parameters must be adjusted reducing data quality

Engineering Contradiction:
Improveimaging velocityVSAvoidimaging parameter precision
Core Design Contradiction:
SpeedVSMeasurement precision

Solution Approach 1:

The patent implements dynamic adjustment of imaging parameters based on the selected contrast phase and imaging velocity requirements. The system dynamically optimizes parameters such as pulse repetition frequency, gain settings, and ROI boundaries to maintain measurement precision while achieving the required imaging velocities for real-time observation

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes imaging parameters according to the specific contrast phase being captured (arterial, venous, delayed) and the desired imaging velocity. By adapting parameters like transmission power, reception gain, and processing algorithms to match the imaging conditions, the system maintains data quality while achieving high-speed imaging

Inventive Principle:
Principle #35Parameter changes

3Loss of information

If complete perfusion process data is captured at high velocity, then diagnostic information completeness is improved, but data volume increases requiring more storage and processing

Engineering Contradiction:
Improveinformation completenessVSAvoiddata volume
Core Design Contradiction:
Loss of informationVSQuantity of substance

Solution Approach 1:

The patent extracts and isolates only the most diagnostically relevant information from the high-velocity imaging data by focusing on specific contrast phases and regions of interest. This extraction process captures complete perfusion information needed for diagnosis while significantly reducing the overall data volume that requires storage and processing

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system performs preliminary data filtering and selection before full processing by pre-defining regions of interest and contrast phase windows. This preliminary action identifies and isolates the essential perfusion data early in the workflow, reducing the volume of data that needs to be fully processed and stored while maintaining complete diagnostic information

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time observation and capture of the complete perfusion process of microbubbles, facilitating reliable diagnostic results by optimizing imaging parameters for different probes and modes.

Implementation Method 1

a planar array probe, a transmitting circuit configured to excite the planar array probe to transmit ultrasonic waves to a target, a receiving circuit configured to control the planar array probe to receive ultrasonic echo signals from the target

Methodology Applied
Scientific EffectUltrasound: Ultrasound

Implementation Method 2

receive ultrasonic echo signals from the target

Methodology Applied
Scientific EffectEcho: Echo

Data Source

PatentUS20260041405A13d/4d contrast-enhanced ultrasound imaging apparatus, methods and media
Publication Date: 2026.02.12 SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
  • US20260041405A1 patent drawing
  • US20260041405A1 patent drawing
  • US20260041405A1 patent drawing

AI summary

Disclosed are 3D/4D contrast-enhanced ultrasound imaging (CEUS) apparatus, 3D/4D CEUS imaging methods and media. The method includes: receiving an input for selecting a 3D/4D contrast-enhanced imaging mode; receiving an input for setting an imaging velocity including a first imaging velocity and a higher second imaging velocity; controlling the apparatus with an imaging parameter associated with the selected imaging mode and the set imaging velocity to achieve imaging with the selected imaging mode in the set imaging velocity, wherein an association between the imaging parameter and the imaging velocity allows that an amount of data required to generate images per volume using the first imaging velocity is greater than that using the second imaging velocity.