7-Dehydrocholesterol Oil Composition for Stable Vitamin D3 Absorption
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Solution Overview
Problem
Existing vitamin D3 compositions extracted from lanolin or lichen contain solvent residues and are not readily absorbed by mammals, prone to lipid oxidation, and deteriorate quickly due to light and UV exposure.
Innovation Solution
An edible oil composition containing 7-dehydrocholesterol and previtamin D3, with specific ratios and additives, stabilizes vitamin D3 content over time and enhances absorption by transforming deteriorated vitamin D3 in situ.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If vitamin D3 is extracted from lanolin or lichen using solvents, then vitamin D3 can be obtained, but solvent residues remain in the finished product and absorption by mammals is poor
Solution Approach 1:
The patent changes the chemical composition parameters by incorporating 7-dehydrocholesterol and previtamin D3 alongside vitamin D3, creating a multi-component composition that improves bioavailability while maintaining vitamin D3 content
Solution Approach 2:
The invention creates a composite oil composition containing vitamin D3, 7-dehydrocholesterol, and previtamin D3 together, where the synergistic combination enhances absorption and stability compared to pure vitamin D3 preparations
2Quantity of substance
If vitamin D3 is extracted from lanolin or lichen, then vitamin D3 can be obtained, but the composition is fragile and prone to oxidation of lipids by oxygen in the air
Solution Approach 1:
The patent introduces 7-dehydrocholesterol and previtamin D3 as intermediary compounds that can transform into vitamin D3 in situ, replacing deteriorated vitamin D3 and maintaining stable concentration over time
Solution Approach 2:
The composition modifies the chemical environment by including specific ratios of 7-dehydrocholesterol (5-30 mg per 100 g) and previtamin D3, which stabilizes the overall composition against oxidation
3Quantity of substance
If the oil composition is exposed to light and UV rays, then vitamin D3 can be formed from 7-dehydrocholesterol, but the oil deteriorates quickly due to formation of free radicals and oxidation chain reactions
Solution Approach 1:
The patent converts the harmful effect of UV light into a beneficial process by using 7-dehydrocholesterol as a precursor that transforms into vitamin D3 upon UV exposure, while the stable composition design mitigates the harmful oxidation effects
4Ease of operation
If the composition contains high amounts of unsaturated lipids, then the oil is more fluid and absorbable, but it is more susceptible to oxidation by oxygen and light
Solution Approach 1:
The patent optimizes the lipid composition parameters by controlling the ratio and type of fatty acids while adding 7-dehydrocholesterol and previtamin D3, achieving a balance between fluidity/absorbability and oxidation stability
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition maintains stable vitamin D3 concentration and improves bioavailability by minimizing oxidation and enhancing absorption, even after prolonged storage and exposure.
Implementation Method 1
these two compounds can be transformed in situ into vitamin D3, replacing vitamin D3 that has deteriorated, in particular through oxidation
Implementation Method 2
prone to lipid oxidation, and deteriorate quickly due to light and UV exposure
Implementation Method 3
UV rays (A, B and C) are known to form free radicals, which give rise to self-sustaining chemical chain reactions
Implementation Method 4
When these compositions are exposed to light, they deteriorate very quickly, even if they are then kept in the dark, due to the rapid formation of activated species (free radicals)
Implementation Method 5
The composition advantageously has a peroxide value of less than 4, in particular less than or equal to 2.5; 2.4; 2.3; 2.2; 2.1; 2; 1.9; 1.8; 1.7; 1.6; 1.5; 1.4; 1.3; 1.2; 1.15, or 1.10 and/or an anisidine value of less than or equal to 1.1; 1.07; 1.05; 1.02; 1.00; 0.97; 0.95; 0.90; 0.87; 0.85; 0.82; 0.80; 0.77; 0.75; 0.72; 0.70; 0.67; 0.65; 0.62; 0.60; 0,57; 0.55; 0.52; 0.50; 0.47; 0.45; 0.43; 0.40; 0.37; 0.35; 0.33; 0.30; 0.27; 0.25; 0.22; 0.20; 0.17; 0.15; 0.12; 0.10; 0.07; 0.05; 0.02
Data Source
AI summary
The present invention relates to an edible oil composition containing vitamin D3, 7-dehydrocholesterol and previtamin D3. According to an implementation of the invention, the edible oil composition contains a mass of 7-dehydrocholesterol per 100 g of composition equal to or greater than one of 5 mg, 10 mg, 15 mg, 20 mg, 21 mg, 22 mg, 23 mg, 23.5 mg, 24 mg, 24.5 mg and 25 mg.