Abdominal Aortic Aneurysm Stress Calculation with Calcification Correction

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Solution Overview

Problem

Current methods for determining stress in anatomical structures, such as the abdominal aorta, are inaccurate due to the lack of patient-specific wall material properties and thickness, and fail to accurately model calcifications, leading to inadequate rupture risk assessment in abdominal aortic aneurysms.

Innovation Solution

A method and apparatus that calculate first stress values based on a range of stiffness and correct second stress values to account for regions with different stiffness, using finite-element modeling and volume meshes to account for calcifications, enabling patient-specific and more accurate stress calculations in anatomical structures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If patient-specific wall material properties and thickness are incorporated into stress calculations, then measurement precision of stress is improved, but device complexity and computational time increase

Engineering Contradiction:
Improvestress measurement precisionVSAvoidmodeling complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The vessel wall is segmented into multiple regions based on stiffness characteristics. Different regions (e.g., calcified vs. non-calcified areas) are assigned different material properties. This segmentation allows patient-specific stress calculations without requiring complete geometric modeling of every detail, thus improving precision while controlling complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different regions of the vessel wall are assigned different material properties based on their local characteristics. Calcified regions are modeled with higher stiffness than non-calcified regions. This local differentiation captures patient-specific variations in wall properties, improving stress measurement precision without requiring uniform complex modeling throughout the entire structure.

Inventive Principle:
Principle #3Local quality

2Measurement precision

If calcifications are accurately geometrically modeled, then measurement precision of stress is improved, but computational time and model complexity increase

Engineering Contradiction:
Improvestress measurement precisionVSAvoidcomputational time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The calcification regions are extracted as separate entities from the overall vessel wall model. Instead of modeling every detail of calcifications within the full geometry, the method identifies calcified regions and applies corrected stress values specifically at these locations. This extraction approach improves precision for critical areas while reducing overall computational time.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

Instead of fully modeling all calcification geometries in detail, the method applies partial correction factors to stress calculations at calcified regions. This partial action approach captures the essential mechanical effect of calcifications on stress distribution without requiring complete geometric representation, thus improving precision while significantly reducing computational time.

Inventive Principle:
Principle #16Partial or excessive action

3Device complexity

If constant thickness and material properties are assumed for the AAA wall, then device complexity is reduced, but measurement precision of stress deteriorates

Engineering Contradiction:
Improvemodeling complexityVSAvoidstress measurement precision
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The method transitions from assuming uniform wall properties to assigning different material properties to different regions. By identifying calcified versus non-calcified regions and assigning appropriate stiffness values to each, the model captures patient-specific variations in wall properties, thereby improving stress measurement precision while maintaining relatively simple modeling assumptions.

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS8150117B2Method and apparatus for determining stress in an anatomical structure
Publication Date: 2012.04.03 KONINKLIJKE PHILIPS NV
  • US8150117B2 patent drawing
  • US8150117B2 patent drawing
  • US8150117B2 patent drawing

AI summary

A method of determining wall stress in an abdominal aortic aneurysm is disclosed. The method includes determining, from anatomical image data, respective first stress values at locations on the wall, based on the aorta having substantially uniform stiffness. The primary direction of stress those locations are determined, and the locations of calcified regions (20) are then determined. The distance to the nearest calcified region is then determined for each location not corresponding to a calcified region, and the additional stress caused by the calcified regions is then determined from values stored in a memory.