Aberration Compensator for Wide-Field OCT-SLO Integration

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Solution Overview

Problem

The integration of Optical Coherence Tomography (OCT) systems with wide-field Scanning Laser Ophthalmoscopes (SLOs) is hindered by optical aberrations and phase effects, which compromise the integrity of the interferometric data and image quality, making it difficult to obtain reliable structural information from the retina.

Innovation Solution

The implementation of an aberration compensator that uses wavefront coding and adaptive optics to correct for aberrations introduced by the scan elements and scan transfer device, ensuring the integrity of the OCT reference and sample beams, and incorporating a variable phase retardation stage to maintain polarization matching, allowing for high-resolution, wide-field imaging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Area of stationary object

If an OCT system is integrated with a wide-field SLO, then structural information can be obtained across the entire retina, but optical aberrations and phase effects compromise the integrity of the interferometric data and image quality

Engineering Contradiction:
Improvefield of viewVSAvoiddata integrity
Core Design Contradiction:
Area of stationary objectVSReliability

Solution Approach 1:

An aberration compensator is introduced as an intermediary component in the optical path between the scan elements and the retina. This compensator corrects optical aberrations and phase effects that would otherwise compromise the interferometric data integrity, enabling reliable OCT imaging across the wide field of view provided by the scan transfer device

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system dynamically adjusts optical parameters including wavefront coding and variable phase retardation to compensate for aberrations introduced by the scan elements. By changing these optical parameters in real-time, the system maintains both the wide field of view and the integrity of the interferometric data

Inventive Principle:
Principle #35Parameter changes

2Area of stationary object

If scan elements and scan transfer device are used to provide wide-field imaging, then ultra-wide field coverage is achieved, but optical aberrations are introduced that disrupt the interferometric data set

Engineering Contradiction:
Improvefield of viewVSAvoidimage quality
Core Design Contradiction:
Area of stationary objectVSManufacturing precision

Solution Approach 1:

The aberration compensator serves as a mediating optical element that corrects the aberrations introduced by the scan elements and scan transfer device. This compensator includes wavefront coding mechanisms and adaptive optics that restore image quality while preserving the ultra-wide field coverage capability

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system incorporates feedback mechanisms that monitor the optical aberrations introduced by the scan elements and dynamically adjust the aberration compensator to correct these aberrations, ensuring consistent image quality across the entire wide field of view

Inventive Principle:
Principle #23Feedback

3Reliability

If wavefront coding and adaptive optics are implemented to correct aberrations, then OCT signal integrity is maintained, but device complexity increases

Engineering Contradiction:
ImproveOCT signal integrityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The aberration compensator is designed to perform multiple functions including wavefront coding, adaptive optics correction, and polarization maintenance within a single integrated optical module. This multi-functionality reduces the overall system complexity compared to implementing separate components for each function

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent combines the aberration correction mechanisms with the existing OCT and SLO optical paths, merging multiple functions into shared optical components. This integration approach maintains OCT signal integrity while minimizing the increase in device complexity

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables the successful integration of OCT with wide-field SLO, providing high-resolution, ultra-wide field imaging capabilities while maintaining the integrity of the OCT signal, thus enhancing diagnostic utility by ensuring accurate structural information across the entire retina.

Implementation Method 1

an aberration compensator that uses wavefront coding and adaptive optics to correct for aberrations introduced by the scan elements and scan transfer device

Methodology Applied
Scientific EffectWavefront coding:

Implementation Method 2

an aberration compensator that uses wavefront coding and adaptive optics to correct for aberrations introduced by the scan elements and scan transfer device

Methodology Applied
Scientific EffectAdaptive optics:

Implementation Method 3

incorporating a variable phase retardation stage to maintain polarization matching

Methodology Applied
Scientific EffectPhase retardation: Phase Modulation

Implementation Method 4

OCT is an interferometric technique whereby an illumination source is directed towards the retina of a subject and the reflected beam, or sample arm, is combined with light in a controlled reference arm and whereby the interference properties of the combined beam are used to determine and display the structure of the imaged retina

Methodology Applied
Scientific EffectInterference: Interference

Implementation Method 5

a source of collimated light and a scanning device which together provide a two-dimensional collimated light scan from an apparent point source

Methodology Applied
Scientific EffectCollimated light:

Data Source

PatentEP2903498B1Improvements in or relating to scanning laser ophthalmoscopes
Publication Date: 2020.12.09 OPTOS PLC
  • EP2903498B1 patent drawingFigure 1
  • EP2903498B1 patent drawingFigure 2
  • EP2903498B1 patent drawingFigure 3

AI summary

A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source (12) of collimated light, a scanning device (14, 16, 1328, 1319), a scan transfer device (20) and a detector (1310). The scan transfer device has a first focus (16) at which an apparent point source is provided and a second focus (24) at which an eye (524, 1324) may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system (900) is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam (902) propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator (1204, 1316) automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.