Absorbance Detector Data Association for Abnormality Diagnosis
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Solution Overview
Problem
Absorbance detectors in liquid chromatography face issues with increased noise and baseline destabilization, making it difficult to identify the cause of abnormalities in analysis results, requiring extensive examinations and prolonged time to clarify issues.
Innovation Solution
An absorbance detector that associates and stores absorbance data with reference signal data, allowing for identification of trends and automatic determination of abnormalities in the sample cell, light source, or optical system, facilitating quicker diagnosis of issues.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If reference signal data is discarded after absorbance calculation, then device complexity is reduced, but ability to diagnose abnormalities is worsened
Solution Approach 1:
The system performs preliminary action by storing reference signal data before it is potentially needed for diagnosis. Instead of discarding the data after absorbance calculation, the system proactively preserves it in association with absorbance data, enabling future abnormality detection without requiring additional data collection during diagnosis.
Solution Approach 2:
The data storage unit acts as an intermediary that maintains the association between reference signal data and absorbance data. This intermediary structure allows diagnostic information to be retrieved and compared without requiring the original measurement conditions to be recreated, facilitating abnormality detection while maintaining data integrity.
2Measurement precision
If extensive examinations are conducted to clarify abnormality causes, then diagnostic accuracy is improved, but time consumption increases
Solution Approach 1:
The system implements feedback by automatically comparing reference signal data with absorbance data to identify abnormalities. This feedback mechanism provides diagnostic information directly from the stored data associations, reducing the need for manual examinations and accelerating the diagnosis process while maintaining accuracy.
Solution Approach 2:
By pre-storing reference signal data in association with absorbance data, the system prepares diagnostic information in advance. When abnormalities occur, the pre-organized data allows for immediate comparison and analysis, eliminating the need for time-consuming retrospective investigations and enabling rapid diagnosis.
3Difficulty of detecting and measuring
If reference signal data is stored in association with absorbance data, then abnormality diagnosis capability is improved, but data storage requirements increase
Solution Approach 1:
The system performs preliminary action by storing reference signal data once during normal operation in association with absorbance data. This one-time storage action eliminates the need for repeated data collection during diagnostic procedures, reducing overall data handling requirements while improving diagnostic capability.
Solution Approach 2:
The stored reference signal data serves multiple functions: it is used for normal absorbance calculations and simultaneously serves as a baseline for abnormality detection and diagnosis. This multi-functionality maximizes the utility of stored data, improving diagnostic capabilities without proportionally increasing storage requirements.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables easy clarification of abnormalities in absorbance data by referencing stored data, reducing the time and effort required to diagnose issues and improving reproducibility of analysis.
Implementation Method 1
a light source for irradiating the sample cell with light, a photo sensor for detecting intensity of light that has been transmitted through the sample
Implementation Method 2
separates light that has been transmitted through the sample cell into wavelength components by a spectrometer
Data Source
AI summary
An absorbance detector includes a sample cell, a light source for irradiating the sample cell, a photo sensor, an optical system for guiding light emitted from the light source to the sample cell and guiding light that has been transmitted through the sample cell to the photo sensor, a reference signal acquirer configured to acquire a detection signal of the photo sensor when the sample solution is not flowing through the sample cell as a reference signal for each analysis of the sample, a calculator configured to find absorbance of the sample based on a measurement signal obtained by the photo sensor in the analysis and the reference signal acquired for the analysis when an analysis of the sample is carried out, and an analysis data storage configured to associate data of the absorbance found by the calculator and data of the reference signal to each other for storage.