Integrated Absorption Collector for Self-Test Analyte Devices
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Solution Overview
Problem
Conventional micro-sample collection and testing devices require additional steps and buffers, leading to increased complexity and cost, particularly in drug self-test applications, where accurate and efficient sampling is crucial.
Innovation Solution
A test device with an integrated sample collector featuring an absorption element that changes states to absorb and release liquid samples automatically, reducing packaging costs and simplifying the sampling process by using a carrier and handle to compress the absorption element, allowing it to interact with the accommodating chamber and release the sample onto the testing area.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If an additional buffer is used to rinse the micro-sample from the collector, then the sample can be transferred to the test device, but the device complexity and packaging cost increase
Solution Approach 1:
The collector is integrated directly with the test device, merging two separate components into one unified structure. The collector body forms part of the test device housing, eliminating the need for separate buffer rinsing steps and reducing overall device complexity while maintaining sample transfer functionality
Solution Approach 2:
The integrated collector serves multiple functions: it collects the micro-sample, stores it, and directly interfaces with the test device for analysis. This multi-functional design eliminates the need for separate buffer rinsing components and simplifies the overall system architecture
2Productivity
If the micro-sample is in direct contact with the label, then the sample can be applied to the test area, but the chemical properties of the label are affected
Solution Approach 1:
A buffer chamber is introduced as an intermediary between the collector and the label area. The buffer fills this chamber and mediates the sample transfer process, allowing the sample to be rinsed and transferred without direct contact between the collector and label, thus preserving label chemical properties while maintaining testing efficiency
3Ease of operation
If an additional pressing structure is used to compress the sample collector, then the sample can be released, but the operation becomes more complex and requires additional steps
Solution Approach 1:
The pressing function is merged with the test device housing structure. The housing itself provides the compression force when the collector is inserted, eliminating the need for separate pressing mechanisms or additional operational steps. The structural design of the housing automatically applies pressure to release the sample upon insertion
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution enables simple, efficient, and cost-effective sampling and testing of analytes in liquid samples, particularly for oral samples, facilitating self-test and point-of-care testing with reduced operational complexity.
Implementation Method 1
an absorption element configured to absorb the liquid sample
Implementation Method 2
the absorption element is compressed to release the liquid to the sample application area
Data Source
AI summary
The present invention provides a device for testing an analyte in a liquid sample, and the device includes: a detection chamber, where the detection chamber is configured to receive a testing element, and the testing element is configured to test the analyte in the liquid sample; and a collector, where an absorption element on the collector is configured to absorb the liquid sample, and the collector is accommodated in the test device. Such device can be used to achieve liquid self-test, for example, collection and self-test of a saliva sample.