Mediator Analysis for Adverse Childhood Experiences and Suicidal Ideation

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Solution Overview

Problem

There is a need to determine mediators that play important roles in the association between adverse childhood experiences and suicidal ideation among older adults, as the relationship between these factors is complex and varies across different age groups.

Innovation Solution

A method is developed to analyze the association between adverse childhood experiences and suicidal ideation in older adults using measured adverse childhood experiences, suicidal ideation, mental health mediators, physical health mediators, social relationship mediators, and covariates. This method includes a data measurement step and a statistical analysis step using logistic-regression analysis and path models to estimate the effects of these mediators.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional research focuses on adolescents and young adults, then the relationship between adverse childhood experiences and suicidal ideation is well-established, but the application to older adults is insufficient due to the considerable time difference and complex developmental processes

Engineering Contradiction:
Improveapplicability of ACE-SI relationship across age groupsVSAvoidstrength of association between ACE and SI in older adults
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent changes the parameter of age group from adolescents/young adults to older adults, and introduces multiple mediator categories (mental health, physical health, social relationship) to account for the complex developmental processes that occur over time. This allows the ACE-SI relationship to be reliably examined in older adults while maintaining theoretical consistency.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces multiple mediator variables (mental health mediators, physical health mediators, social relationship mediators) between adverse childhood experiences and suicidal ideation in older adults. These mediators serve as intermediaries that explain the complex relationship over time, resolving the contradiction between the time difference and the strength of association.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Loss of information

If multiple mediators are introduced to analyze the complex relationship between ACE and SI in older adults, then the understanding of underlying mechanisms is improved, but the complexity of the analysis increases

Engineering Contradiction:
Improveunderstanding of underlying mechanismsVSAvoidcomplexity of statistical analysis
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent segments the mediators into three distinct categories: mental health mediators, physical health mediators, and social relationship mediators. This segmentation allows the complex relationship between ACE and SI to be analyzed systematically by examining each mediator category separately, reducing the overall complexity while maintaining comprehensive understanding.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent adds multiple dimensions of analysis by introducing different types of mediators (mental, physical, social relationship) alongside the traditional ACE-SI relationship. This dimensional expansion allows for a more comprehensive understanding of underlying mechanisms without overwhelming complexity, as each dimension can be analyzed independently through path models.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentUS20250143613A1Method for Determining Meditators of the Association between Adverse Childhood Experiences and Suicidal Ideation in Late Adulthood and Computing Device for Implementing the Method
Publication Date: 2025.05.08 YONSEI UNIV WONJU IND ACADEMIC COOP FOUND
  • US20250143613A1 patent drawing
  • US20250143613A1 patent drawing
  • US20250143613A1 patent drawing

AI summary

A method for determining mediators on the association between adverse childhood experiences and suicidal ideation of older adults according to an embodiment of the present disclosure, which is a method for determining mediators on the association between adverse childhood experiences of older adults, as an independent variable, and suicidal ideation, as a dependent variable, may include a data measurement step of measuring data for adverse childhood experiences, suicidal ideation, mental health mediators, physical health mediators, social relationship mediators, and covariates; and a statistical analysis step of estimating adjusted effects and crude effects of the mental health mediators, physical health mediators, and social relationship mediators on the suicidal ideation using a logistic-regression analysis and analyzing three path models respectively using mental health mediators, physical health mediators, and social relationship mediators, which are sets of multiple mediators.