Acetic Acid Composition with Butyric Acid and Quercetin for Flavor Masking

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Solution Overview

Problem

There is a need for novel and improved compositions comprising vinegar with enhanced nutritional value and biological activity to address health benefits such as cancer, inflammatory diseases, metabolic disorders, obesity, diabetes, high blood pressure, and vascular diseases, while masking the off-flavor derived from acetic and butyric acids.

Innovation Solution

A composition comprising between 50% and 95% acetic acid, 0.1% to 5% butyric acid or its derivative, and 0.1% to 5% quercetin or its derivative, optionally with a fruit or vegetable material, formulated to achieve a specific weight ratio and method of preparation that enhances stability and biological activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If vinegar is used as a health supplement, then health benefits are provided, but off-flavor is generated

Engineering Contradiction:
Improvehealth benefitsVSAvoidoff-flavor
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies this principle by combining acetic acid (the harmful off-flavor source) with butyric acid and quercetin in specific ratios. The butyric acid and quercetin mask the unpleasant taste of acetic acid while the combination provides synergistic health benefits, converting the harmful off-flavor into a beneficial multi-component formulation.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent creates a composite formulation containing acetic acid, butyric acid, and quercetin in specific weight ratios (0.1-5% butyric acid, 0.1-5% quercetin, and 50-95% acetic acid). This composite material combines the harmful off-flavor source with beneficial components to create a product that maintains health benefits while improving palatability.

Inventive Principle:
Principle #40Composite materials

2Reliability

If acetic acid concentration is increased, then health benefits are enhanced, but stability is reduced

Engineering Contradiction:
Improvehealth benefitsVSAvoidcomposition stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent applies parameter changes by optimizing the concentration ratios of acetic acid, butyric acid, and quercetin. By maintaining acetic acid at 50-95% while adding specific amounts of butyric acid (0.1-5%) and quercetin (0.1-5%), the formulation achieves both high health benefit potential and improved compositional stability through the buffering and protective effects of the additional components.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The high concentration acetic acid formulation is stabilized by creating a composite material system where butyric acid and quercetin act as stabilizing agents. The specific ratio ranges provided in the patent ensure that the composite maintains stability while delivering enhanced health benefits from the high acetic acid content.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentEP4360467A1Compositions comprising acetic acid, butyric acid and quercetin and uses thereof
Publication Date: 2024.05.01 COMTEMP CO DOS TEMPEROS LDA
  • EP4360467A1 patent drawingFigure 1~2
  • EP4360467A1 patent drawingFigure 3~4A
  • EP4360467A1 patent drawingFigure 4B~5A

AI summary

The present disclosure is directed to compositions comprising between 50% and 95% weight per weight (w/w) of acetic acid, between 0.1% and 5% (w/w) of butyric acid or a derivative thereof, and between 0.1% and 5% (w/w) of quercetin or a derivative thereof. Further, methods of use such as for the treatment and prevention of a medical condition associated with cancer, inflammatory diseases or disorders, metabolic disorders, obesity, diabetes, high blood pressure, vascular diseases, viral infection, and any combination thereof, in a subject in need thereof are also provided.