Acetone Acidic Extraction Solvent for Pesticide Residue Analysis
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Solution Overview
Problem
Current methods for detecting pesticide residues in agricultural products using rapid extraction kits rely on toxic solvents like acetonitrile, which pose environmental and health risks, and require a solvent exchange step for GC/MS-MS detection.
Innovation Solution
A residual pesticide extraction combination liquid comprising an acidic solution (0.5 to 3 vol %) and an acetone solution is used for rapid extraction, eliminating the need for acetonitrile and allowing direct input into chromatography instruments.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If acetonitrile solution is used as extraction solvent, then extraction efficiency is improved, but environmental pollution and health risks increase
Solution Approach 1:
The patent changes the chemical composition parameters of the extraction solvent from acetonitrile-based to acetone-based with acidic solution (0.5-3 vol%), maintaining extraction efficiency while eliminating toxic effects. This parameter substitution resolves the contradiction between productivity and harmful factors.
Solution Approach 2:
The patent employs a disposable rapid extraction kit containing pre-packaged acetone-based extraction solvent and mixed powder (graphite carbon and anhydrous sodium sulfate). This disposable system eliminates the need for repeated solvent purification and disposal procedures, reducing environmental impact while maintaining extraction efficiency.
2Speed
If acetonitrile-containing solvent is used for extraction, then extraction speed is improved, but additional solvent exchange step is required
Solution Approach 1:
The patent changes the solvent type from acetonitrile to acetone, which is compatible with GC/MS-MS detection without requiring solvent exchange. This parameter change eliminates the additional processing step while maintaining rapid extraction speed.
Solution Approach 2:
The patent extracts and removes the problematic acetonitrile component from the extraction system, replacing it with acetone that does not require further removal or exchange before detection. This extraction of the harmful element simplifies the overall process.
3Productivity
If rapid extraction kit is used, then detection speed is improved, but toxic solvent usage increases
Solution Approach 1:
The patent changes the solvent composition parameter in the rapid extraction kit from toxic acetonitrile to less harmful acetone with acidic solution, maintaining the rapid detection capability while reducing toxic solvent usage and associated environmental and health risks.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This method effectively extracts pesticide residues with high recovery rates (>70% for 178 pesticides) while avoiding toxic solvents, reducing environmental impact, and simplifying the detection process.
Implementation Method 1
mixing the residual pesticide extraction combination liquid described in the present invention with the homogenized sample to form a sample solution
Implementation Method 2
add an extraction solvent to the homogenized agricultural sample to extract the primary test liquid
Data Source
AI summary
A pesticide residue extraction solution adapted for a rapid extraction method of stock solution of agricultural products and a pesticide residue detection method in agricultural products. The pesticide residue extraction solution includes acidic solution and acetone solution. The rapid extraction method includes homogenizing the agricultural product sample, to obtain a homogenized sample; mixing the pesticide residue extraction solution with the homogenized sample to form a sample solution; and subsequently using a column filled with mixed powder to filter out the water and impurities from the sample solution, thereby obtaining a stock solution of the agricultural product. The method for detecting agricultural product pesticide residues includes using the rapid extraction method to obtain the stock solution of agricultural product, and to directly input the stock solution of the agricultural product into a liquid chromatography tandem mass spectrometer or a gas chromatography tandem mass spectrometer for pesticide residue detection.