Acid-Stable Serine Proteases in Vaccinated Broiler Feed
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Solution Overview
Problem
Coccidiosis vaccination in poultry leads to reduced performance, including weight gain and feed efficiency, due to decreased feed intake and nutrient absorption, posing significant economic challenges for broiler producers.
Innovation Solution
Incorporating acid-stable serine proteases into the diet of vaccinated birds, particularly serin proteases, which improve weight gain and Feed Conversion Ratio (FCR) by enhancing nutrient absorption and overcoming the negative effects of coccidiosis vaccination.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If coccidiosis vaccination is administered to broiler chickens, then protection against coccidiosis is achieved, but feed intake and weight gain are reduced
Solution Approach 1:
Acid-stable proteases are introduced as intermediary substances in the feed to mediate between the vaccine-induced immune response and nutrient absorption. These enzymes break down proteins into smaller peptides and amino acids that can be absorbed more efficiently, compensating for the reduced feed intake caused by vaccination while maintaining protection against coccidiosis
Solution Approach 2:
The invention changes the biochemical parameters of feed digestion by adding acid-stable proteases that remain active in the acidic environment of the poultry gut. This enzymatic enhancement modifies the digestion efficiency parameter, allowing better nutrient extraction from feed despite reduced consumption volumes following vaccination
2Reliability
If coccidiosis vaccination is administered to broiler chickens, then protection against coccidiosis is achieved, but feed efficiency is reduced
Solution Approach 1:
Acid-stable proteases serve as intermediary agents that improve the conversion of feed into usable nutrients. By enhancing protein breakdown and amino acid availability in the digestive tract, these enzymes act as mediators that improve feed efficiency ratios, allowing vaccinated birds to achieve better growth performance per unit of feed consumed
Solution Approach 2:
The addition of acid-stable proteases changes the digestive efficiency parameters by increasing the proportion of digestible nutrients. This biochemical modification improves the feed conversion ratio, addressing the reduced feed efficiency observed in vaccinated broiler chickens
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The use of acid-stable serine proteases significantly improves the performance of broiler chickens by increasing weight gain and reducing Feed Conversion Ratio, thereby mitigating the economic impact of coccidiosis vaccination.
Implementation Method 1
Incorporating acid-stable serine proteases into the diet of vaccinated birds, particularly serin proteases, which improve weight gain and Feed Conversion Ratio (FCR) by enhancing nutrient absorption
Data Source
AI summary
The invention relates to the use of at least one acid stable protease in poultry feed in combination with anti-coccidial vaccination of birds for increasing the performance of vaccinated animals. It has been found surprisingly that the additions of at least one acid stable protease according to the invention to the diet of "cocci"-vaccinated birds have a significant improvement of animal performance. The inventors found that especially the use of serin proteases improve the performance of vaccinated broiler chickens, in particular the use of serin proteases increases weight gain and improves Feed Conversion Ratio (FCR) of cocci-vaccinated birds.