Acne Treatment Composition with Skin-Bonding Polymer Sustained Release

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Solution Overview

Problem

Current acne treatments often provide temporary relief and can cause skin irritation due to the rapid release of anti-acne components, necessitating a composition that offers sustained release of anti-acne properties over an extended period without irritating the skin.

Innovation Solution

An acne treatment composition incorporating an effective amount of an anti-acne component and a skin bonding polymer component, which forms a hydrophobic polymer/hydrophilic polymer adduct to provide sustained release of the anti-acne component over a prolonged period, typically at least one hour, by binding to the skin and maintaining proximity to the skin tissue.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a large dose of anti-acne active component is applied to provide effective anti-acne properties, then the anti-acne effect is improved, but skin tissue irritation increases

Engineering Contradiction:
Improveanti-acne effectVSAvoidskin tissue irritation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The polymer component is applied first to bind to the skin tissue, creating a reservoir that gradually releases the anti-acne active component. This preliminary action allows the active component to be delivered over time rather than all at once, reducing peak concentration and irritation while maintaining therapeutic effect.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The formulation changes the release rate parameter of the anti-acne active component from rapid to sustained release. By controlling the release kinetics through the polymer matrix, the concentration of the active component at the skin surface is maintained at therapeutic levels without causing irritation from high peak concentrations.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If conventional acne treatment compositions are applied, then anti-acne properties are provided, but the duration of action is short requiring frequent reapplication

Engineering Contradiction:
Improveanti-acne propertiesVSAvoidduration of anti-acne action
Core Design Contradiction:
ReliabilityVSDuration of action of moving object

Solution Approach 1:

The polymer component binds to the skin tissue in advance, creating a reservoir that gradually releases the anti-acne active component over an extended period. This preliminary binding action ensures continuous presence of the active component at the treatment site without requiring frequent reapplication.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The formulation provides continuous release of the anti-acne active component from the polymer-bound reservoir on the skin. This continuous action maintains therapeutic levels of the active component over many hours, eliminating the need for frequent reapplication while sustaining anti-acne efficacy.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves prolonged anti-acne properties, reducing the frequency of application and minimizing skin irritation by maintaining a consistent release of the anti-acne component, thereby enhancing the treatment's effectiveness and comfort.

Implementation Method 1

a skin bonding polymer component to provide sustained release of the anti-acne component over a prolonged period of time after application of the acne treatment composition to skin tissue

Methodology Applied
Scientific EffectHydrophobic polymer/hydrophilic polymer adduct formation:

Implementation Method 2

provide sustained release of the anti-acne component over a prolonged period of time

Methodology Applied
Scientific EffectSustained release:

Data Source

PatentUS9149490B2Acne treatment composition and methods for using
Publication Date: 2015.10.06 SKINVISIBLE PHARMACEUTICALS INC
  • US9149490B2 patent drawing
  • US9149490B2 patent drawing
  • US9149490B2 patent drawing

AI summary

An acne treatment composition is provided according to the present invention. The acne treatment composition includes an effective amount of an anti-acne component to provide anti-acne properties to skin tissue, an effective amount of a skin bounding polymer component to provide sustained release of the anti-acne component over a prolonged period of time after application of the acne treatment composition to skin tissue, and water. A method of using an acne treatment composition is provided.