Acoustic Fluid Delivery for Mucosal Elevation
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Solution Overview
Problem
Conventional needle injection methods for delivering fluids during mucosa resection are unselective, lead to rapid fluid escape, and cause thermal damage and perforation, making it difficult to maintain fluid retention and accurately target tissue layers.
Innovation Solution
A surgical instrument that introduces liquid under the mucosal layer without a needle, using a water jet for selective tissue elevation and separation, combined with high-frequency surgery capabilities for coagulation and resection, allowing for improved fluid retention and precise tissue handling.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If conventional needle injection methods are used to deliver liquid under the mucosa, then fluid can be introduced to elevate tissue, but the fluid escapes rapidly and requires frequent re-injection
Solution Approach 1:
The patent replaces the mechanical needle injection system with an acoustic field-based system. High-intensity focused ultrasound (HIFU) waves are used to create acoustic radiation pressure that pushes liquid through the mucosa and into the submucosal layer without physical contact, thereby eliminating needle trauma and achieving prolonged fluid retention
Solution Approach 2:
The patent utilizes the phase transition properties of acoustic waves. The HIFU waves undergo phase transitions as they propagate through tissue, creating zones of high and low pressure that facilitate selective fluid delivery and retention in the submucosal layer without rapid escape
2Measurement precision
If conventional needle injection is used to precisely place liquid in the submucosal layer, then fluid delivery can be attempted, but tactile feel is required and complete perforation of target tissue can occur
Solution Approach 1:
The patent replaces mechanical needle insertion with a non-contact acoustic field system. HIFU waves can be precisely focused on the submucosal layer without mechanical trauma, eliminating the risk of complete tissue perforation and reducing thermal damage compared to needle-based methods
Solution Approach 2:
The patent introduces acoustic waves as an intermediary between the operator and the target tissue. The HIFU waves serve as a mediator that can selectively deliver energy and fluid to the submucosal layer without direct mechanical contact, thereby avoiding the harmful effects of needle perforation
3Quantity of substance
If liquid is injected under the mucosa to create a fluid pocket, then tissue elevation can be achieved, but the liquid accumulates without integrating with the submucosal tissue matrix and escapes rapidly
Solution Approach 1:
The patent replaces mechanical needle injection with acoustic field-based fluid delivery. The HIFU-generated acoustic radiation pressure creates controlled fluid flow that promotes integration with the submucosal tissue matrix rather than simple accumulation, resulting in stable fluid retention without rapid escape
4Productivity
If high-frequency surgery is combined with liquid injection for tissue resection, then coagulation and cutting can be performed, but thermal damage to surrounding tissues can occur
Solution Approach 1:
The patent applies the principle of local quality by using HIFU to create highly localized thermal zones. The acoustic energy is focused precisely on the target tissue for coagulation and cutting, while surrounding tissues remain unaffected due to the localized nature of acoustic energy deposition
Solution Approach 2:
The patent uses acoustic waves as an intermediary to deliver thermal energy selectively. The HIFU waves act as a mediator that can heat and coagulate target tissue without directly contacting it, thereby reducing thermal damage to surrounding structures compared to direct contact methods
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The instrument enables efficient and precise tissue elevation and separation with improved fluid retention, reducing the need for frequent re-injection and minimizing thermal damage to surrounding tissues, thus enhancing the safety and efficiency of mucosa resection procedures.
Implementation Method 1
The liquid is selectively transported and diffuses throughout the submucosal tissue matrix when delivered at a suitable pressure
Implementation Method 2
The surgical instrument may further comprise a device for high frequency surgery
Data Source
AI summary
A method for the selective elevation and separation of tissues comprised of multiple layers and a surgical instrument for performing the method. The method may be performed without the requirement of a solid mechanical device insertion or transection through the mucosal layer. In particular, the method and surgical instrument may be used for the selected separation and/or resection of selected portions of benign or malignant tissues (e.g. defining tissue planes, polyp elevation and removal, submucosal tissue tunnelling, endoscopic mucosa resection, etc).