Low-Energy Acoustic Shock Wave Glandular Modulation
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Solution Overview
Problem
Current acoustic shock wave therapies for modulating glandular hormonal secretions are limited in their ability to provide sustained hormonal regulation and often require frequent treatments, with existing methods either being invasive or causing discomfort due to high energy focal points.
Innovation Solution
The use of low-energy acoustic shock waves, either focused or unfocused, is applied to specific glands using an acoustic shock wave generator, which stimulates hormonal modulation by increasing or decreasing hormone release, and is complemented by a 3D ultrasound system for precise targeting, allowing for longer periods between treatments with reduced discomfort.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If high energy focused acoustic shock waves are used to stimulate glands, then hormonal modulation effect is improved, but patient discomfort and pain increase
Solution Approach 1:
The patent changes the energy parameter from high to low (0.01-0.4 mJ/mm²) while maintaining the therapeutic effect through increased number of pulses (100-2000 pulses per session). This parameter transformation resolves the contradiction by substituting energy intensity with treatment duration and pulse count to achieve the same hormonal modulation without causing pain or discomfort.
2Reliability
If frequent treatments are administered to maintain hormonal regulation, then therapeutic effectiveness is improved, but treatment time and patient burden increase
Solution Approach 1:
The low energy acoustic shock wave treatment performs preliminary stimulation that triggers sustained hormonal regulation effects lasting longer between treatments. By delivering multiple pulses (100-2000) in each session at low energy, the treatment creates a prolonged biological response that reduces the need for frequent repeat treatments compared to high energy methods.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach effectively modulates hormonal secretions, reduces treatment frequency, and minimizes discomfort by using low-energy shock waves that stimulate cellular responses without causing pain, promoting vascularization and hormonal balance with fewer side effects.
Implementation Method 1
The emitted acoustic shock waves are focused or unfocused acoustic shock waves, or acoustic pressure waves, generated electrohydraulically
Implementation Method 2
The emitted acoustic shock waves are focused or unfocused acoustic shock waves, or acoustic pressure waves, generated electrohydraulically, electromagnetically
Implementation Method 3
The emitted acoustic shock waves are focused or unfocused acoustic shock waves, or acoustic pressure waves, generated electrohydraulically, electromagnetically, radially, or via a piezo electric generating system
Implementation Method 4
acoustic shock waves cause a cells membrane to become permeable allowing for the exchange of certain proteins with surrounding cells
Implementation Method 5
The stimulating of the gland causes a release of nitric oxide and growth factors including, but not limited to vascular endothelial growth factor (VEGF)
Implementation Method 6
These releases stimulate a biologic cascade that includes the recruitment and activation of stem cells, including localized stem cells, and those recruited from a bodies own bone marrow and fat deposits
Implementation Method 7
shock waves modulate the inflammatory system via the toll like receptor 3 channels (TLR3)
Data Source
AI summary
A method of modulating glandular secretions by administering acoustic shock waves to a gland, includes the steps of activating acoustic shock waves of an acoustic shock wave generator to emit acoustic shock waves and subjecting the gland to acoustic shock waves stimulating the gland to have a modulated response. The modulated response is one of an adjustment in hormonal release which increases low level output, decreases high level output or stabilizes erratic output. The emitted acoustic shock waves are focused or unfocused low energy acoustic shock waves. The gland underlies the patient's skin. The shock wave generator is acoustically coupled to the patient's skin using a coupling gel or liquid. The gland is one of a testicle, ovary, pituitary gland, adrenal gland, thyroid gland, thymus, pineal gland, parathyroid, or hypothalamus. The method can be repeated one or more times.