Acrylamide Production Biocatalyst Startup

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Solution Overview

Problem

The existing methods for continuously producing acrylamide using a biocatalyst result in a diluted acrylamide solution that takes time to reach the desired concentration, necessitating concentration or recycling processes, increasing costs and operational complexity.

Innovation Solution

A method involving continuous reactions in multiple connected reaction vessels, where acrylamide is introduced into the first vessel before initiating reactions, with controlled flow rates and biocatalyst concentrations to achieve the desired acrylamide concentration levels efficiently.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If water is introduced into the reaction vessel in advance of initiating continuous reactions, then the reaction can start smoothly, but the produced acrylamide is diluted and the concentration remains lower than desired for some time

Engineering Contradiction:
Improvesmooth reaction startVSAvoidacrylamide concentration
Core Design Contradiction:
Ease of operationVSQuantity of substance

Solution Approach 1:

The patent applies preliminary action by introducing a concentrated acrylamide solution into the reaction vessel before starting the continuous reaction. This pre-introduced solution serves as a head start, ensuring that the effluent concentration reaches the desired level quickly without requiring extensive dilution or concentration adjustments during operation.

Inventive Principle:
Principle #10Preliminary action

2Quantity of substance

If the acrylamide solution concentration is lower than desired, then concentration or recycling processes are necessary, but this increases production costs and operational complexity

Engineering Contradiction:
Improveacrylamide concentrationVSAvoidconcentration or recycling equipment
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

By pre-introducing concentrated acrylamide solution, the system achieves desired concentration levels immediately upon starting continuous operation, eliminating the need for downstream concentration equipment or recycling loops that would otherwise be required to correct dilution.

Inventive Principle:
Principle #10Preliminary action

3Quantity of substance

If the acrylamide solution concentration is lower than desired, then additional concentration or recycling processes are needed, but this increases operational procedures complexity

Engineering Contradiction:
Improveacrylamide concentrationVSAvoidoperational procedures
Core Design Contradiction:
Quantity of substanceVSEase of operation

Solution Approach 1:

The pre-introduction of concentrated acrylamide solution simplifies operational procedures by ensuring that the desired concentration is achieved automatically at the start of continuous operation, eliminating the need for operators to manage additional concentration or recycling processes.

Inventive Principle:
Principle #10Preliminary action

4Quantity of substance

If multiple reaction vessels are used with acrylamide introduced in advance, then the desired concentration is achieved quickly, but the system complexity increases

Engineering Contradiction:
Improveacrylamide concentrationVSAvoidmultiple reaction vessels system
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent segments the reaction system into multiple串联 reaction vessels, with concentrated acrylamide solution introduced into the first vessel. This segmentation allows the concentration profile to be controlled through the series, achieving desired effluent concentration while distributing the system complexity across modular units.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

By pre-introducing concentrated acrylamide solution into the first reaction vessel of the series, the system establishes the necessary concentration baseline that propagates through subsequent vessels, enabling quick achievement of desired effluent concentration without requiring complex control mechanisms.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for the continuous retrieval of an acrylamide solution at the desired concentration shortly after initiating reactions, reducing production costs and simplifying procedures.

Implementation Method 1

a biocatalyst to produce acrylamide continuously from acrylonitrile

Methodology Applied
Scientific EffectEnzymatic hydration: Enzyme

Implementation Method 2

hydrating the acrylonitrile using a biological catalyst

Methodology Applied
Scientific EffectHydration reaction: Hydrolysis

Data Source

PatentEP2930243B1Method for producing acrylamide
Publication Date: 2020.12.23 MITSUBISHI CHEM CORP
  • EP2930243B1 patent drawing
  • EP2930243B1 patent drawing
  • EP2930243B1 patent drawing

AI summary

Provided is a method that is for producing acrylamide, continuously produces acrylamide from acrylonitrile using a biocatalyst, and is characterized in that a continuous reaction is started by means of introducing acrylamide into a reaction vessel and then causing acrylonitrile to contact a biocatalyst. The method for producing acrylamide has superior operability and a low cost, and is capable of continuously extracting an aqueous solution of acrylamide at a target concentration in a short period of time after starting the continuous reaction.