Automated ACS Therapy System for Intra-Abdominal Pressure Control

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Solution Overview

Problem

Current methods for managing fluid resuscitation in trauma patients often result in oliguria or anuria, leading to elevated intra-abdominal pressure and potentially life-threatening Abdominal Compartment Syndrome, as there is a lack of continuous and automatic monitoring and intervention systems to balance fluid input and output effectively.

Innovation Solution

An automated ACS therapy system that includes an IAP monitor connected to a urine withdrawal device, an abdominal fluid removal device, and a fluid control system, which uses an active feedback loop to regulate intra-abdominal pressure by controlling fluid and diuretic administration, and fluid removal from the abdominal cavity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If fluid resuscitation is administered to maintain blood pressure and vascular function, then cardiovascular stability is improved, but intra-abdominal pressure increases leading to Abdominal Compartment Syndrome

Engineering Contradiction:
Improvecardiovascular stabilityVSAvoidintra-abdominal pressure
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The system continuously monitors intra-abdominal pressure via bladder pressure measurements and uses this feedback to automatically regulate fluid resuscitation rates, diuretic administration, and abdominal fluid removal, creating a closed-loop control system that prevents IAP from reaching dangerous levels while maintaining cardiovascular stability

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system enables the patient's own physiological systems to self-regulate by automatically adjusting fluid balance through monitored urine output and automated diuretic delivery, reducing the need for external manual intervention and allowing the body to maintain its own fluid homeostasis

Inventive Principle:
Principle #25Self-service

2Measurement precision

If manual bladder pressure measurements are performed ad-hoc, then diagnostic information is obtained, but continuous monitoring and automatic intervention are not achieved

Engineering Contradiction:
Improvebladder pressure measurementVSAvoidautomatic therapy
Core Design Contradiction:
Measurement precisionVSExtent of automation

Solution Approach 1:

The system transforms manual ad-hoc pressure measurements into continuous automated monitoring by connecting the bladder pressure transducer to a computer that continuously reads and processes IAP data, automatically adjusts therapy parameters, and triggers interventions without manual input, achieving both precise measurement and full automation

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system replaces manual mechanical pressure measurement and assessment with an automated electronic monitoring system that uses computer algorithms to continuously process pressure data, calculate fluid balance, and automatically control therapy delivery, eliminating the need for repeated manual measurements

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If fluid resuscitation is increased to prevent organ collapse, then vascular function is maintained, but fluid overload occurs causing elevated intra-abdominal pressure

Engineering Contradiction:
Improvevascular functionVSAvoidfluid volume
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The system continuously monitors both fluid input and output (urine production) along with bladder pressure, using this feedback to dynamically adjust fluid resuscitation rates and automatically remove abdominal fluid when pressure becomes elevated, preventing fluid overload while maintaining vascular function

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system dynamically changes fluid management parameters based on real-time conditions, automatically adjusting fluid resuscitation rates, diuretic dosing, and abdominal fluid removal based on monitored IAP levels and urine output, optimizing fluid balance for each patient's specific physiological state

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables continuous and minimally-invasive management of fluid resuscitation, preventing the onset of Abdominal Compartment Syndrome by maintaining a balanced fluid status and automatically adjusting fluid and diuretic delivery based on real-time IAP measurements, thereby reducing the risk of organ dysfunction.

Implementation Method 1

measurement of bladder pressure has become the method of choice because bladder pressure can be easily and reliably measured by using a conventional pressure transducer or monitor

Methodology Applied
Scientific EffectPressure transduction:

Implementation Method 2

The abdominal fluid removal device may be connected to an active suction device, which withdraws fluid from the abdominal cavity through the abdominal fluid removal device when activated

Methodology Applied
Scientific EffectSuction: Suction

Data Source

PatentUS8403884B2ACS therapy system
Publication Date: 2013.03.26 CR BARD INC
  • US8403884B2 patent drawing
  • US8403884B2 patent drawing
  • US8403884B2 patent drawing

AI summary

An ACS therapy system for continuously monitoring Intra-Abdominal Pressure (IAP) and preventing the onset of ACS. The automated ACS therapy system includes a urine withdrawal device, an IAP regulation circuit, an IAP monitor connected to the urine withdrawal device to supply an IAP value to the IAP regulation circuit, and an abdominal fluid removal device. The abdominal fluid removal device may be connected to an active suction device, which withdraws fluid from the abdominal cavity through the abdominal fluid removal device when activated by the IAP regulation circuit. Based on the IAP value, the IAP regulation circuit may send a control signal that controls the active suction device to turn on and drain fluid from the abdominal cavity. When the IAP value reaches certain levels, the IAP regulation circuit may cause the active suction device to be turned off.