Active Compound Combinations for Plant-Compatible Pest Control

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Solution Overview

Problem

Existing acaricidal and insecticidal compounds exhibit unsatisfactory efficacy and compatibility with plants, particularly crop plants, necessitating the development of novel active compound combinations with improved properties.

Innovation Solution

A combination of compounds of formula (I) with specific substituents and at least one active compound from Biological Control Agent (BCA) Groups (1) to (7) for enhanced insecticidal, acaricidal, and nematicidal properties, exhibiting synergistic effects against animal and microbial pests, and acting as plant strengthening agents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If known compounds of formula (I) are used for insecticidal control, then some insecticidal activity is achieved, but the acaricidal efficacy and compatibility with plants are unsatisfactory

Engineering Contradiction:
Improveacaricidal efficacyVSAvoidcompatibility with plants
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines compounds of formula (I) with biological control agents (BCAs) from groups (1) to (7) to create synergistic mixtures. This merging approach leverages the complementary strengths of both components: the insecticidal activity of formula (I) compounds and the broad-spectrum biological control properties of BCAs, thereby improving overall acaricidal efficacy and plant compatibility simultaneously

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates composite active substance combinations by integrating chemical compounds of formula (I) with biological control agents. This composite approach produces a multi-functional formulation that exhibits enhanced insecticidal, acaricidal, and nematicidal properties while maintaining better compatibility with crop plants compared to single-component products

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If known compounds of formula (I) are used for pest control, then some insecticidal action is achieved, but the activity spectrum and compatibility with plants are insufficient

Engineering Contradiction:
Improveactivity spectrumVSAvoidcompatibility with plants
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The combination of formula (I) compounds with biological control agents creates a multi-functional product that targets multiple pest types (insects, acarids, nematodes) and provides both direct toxic effects and plant strengthening actions. This universal approach expands the activity spectrum while maintaining plant compatibility through the beneficial effects of BCAs

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If single active ingredients are used, then the formulation is simple, but the synergistic effect and overall pest control efficacy are limited

Engineering Contradiction:
Improvesynergistic effectVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges compounds of formula (I) with biological control agents to create synergistic mixtures. This combining approach produces enhanced pest control efficacy that exceeds the sum of individual components, achieving superior insecticidal, acaricidal, and nematicidal effects while the formulation remains practically manageable

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS20250287949A1Active compound combinations having insecticidal/acaricidal properties
Publication Date: 2025.09.18 BAYER AG
  • US20250287949A1 patent drawing
  • US20250287949A1 patent drawing
  • US20250287949A1 patent drawing

AI summary

The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) and at least one further active compound of the formula (II), which combinations are highly suitable for controlling animal and microbial pests such as unwanted insects and/or unwanted acarids and/or unwanted nematodes.