Active-Escape Bias Assessment Apparatus Using Bayesian Learning Variables

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Solution Overview

Problem

Current methods for assessing active-escape bias in mammals are limited in their ability to accurately predict behavioral responses and diagnose medical conditions, particularly in relation to suicidal tendencies, due to the complexity of integrating computational and metabolic resource management within the active inference framework.

Innovation Solution

A method and apparatus that utilize a series of cues and aversive physical stimuli to elicit specific response states in mammals, with probabilistic functions determining the duration and application of stimuli, allowing for the classification of active-escape bias through learning variables and standardized scores, incorporating structured Bayesian models and neuromodulatory parameters.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a series of cues and aversive physical stimuli are used to elicit response states, then the ability to predict active-escape bias and diagnose medical conditions is improved, but the complexity of integrating computational and metabolic resource management increases

Engineering Contradiction:
Improveprediction accuracy of active-escape biasVSAvoidcomplexity of computational and metabolic resource integration
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The assessment method segments the complex behavioral assessment into distinct response states (active-escape, passive-escape, active-avoid, passive-avoid) that can be independently measured and analyzed. Each response state corresponds to specific combinations of cue presence/absence and stimulus application, allowing the complex problem of active-escape bias measurement to be broken down into manageable, discrete components that can be evaluated separately and then integrated through Bayesian modeling.

Inventive Principle:
Principle #1Segmentation

2Reliability

If probabilistic functions are used to determine stimulus duration and application, then the sensitivity and specificity of diagnostic assessments are improved, but the computational resources required increase

Engineering Contradiction:
Improvesensitivity and specificity of diagnostic assessmentVSAvoidcomputational resource consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The method employs probabilistic functions that dynamically adjust stimulus duration and application parameters based on the subject's responses and the specific response state being elicited. By varying these parameters probabilistically rather than using fixed values, the system optimizes the balance between gathering sufficient diagnostic information (improving sensitivity and specificity) and managing computational and metabolic resources efficiently.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If learning variables and standardized scores are calculated from physical signals, then the ability to classify active-escape bias is improved, but the time required for data transformation and analysis increases

Engineering Contradiction:
Improveclassification accuracy of active-escape biasVSAvoidtime for data transformation and analysis
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The methodology pre-establishes the transformation framework and Bayesian models before actual data collection begins. The learning variables and standardized scores are defined in advance with their corresponding calculation procedures, allowing for efficient real-time or near-real-time processing of physical signals during the assessment. This preliminary preparation reduces the computational burden during actual data analysis and minimizes the time required to transform raw physical signals into meaningful classification results.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20240285207A1Apparatus and method for assessing active-escape bias in mammals
Publication Date: 2024.08.29 CENT FOR ADDICTION & MENTAL HEALTH
  • US20240285207A1 patent drawing
  • US20240285207A1 patent drawing
  • US20240285207A1 patent drawing

AI summary

A series of cues are provided to mammalian subject in association with a predetermined pattern of response states. Responsive to each cue, a physical signal of actuation, or non-actuation within a predetermined time from initiation of the cue, is received and recorded in association with the respective response state. Each response state is an active-escape state, a passive-escape state, an active-avoid state, or a passive-avoid state. The predetermined pattern includes a plurality of sequences and at least one reversal. The physical signals are transformed according to a predefined model incorporating the predetermined pattern to obtain at least one learning variable of the mammalian subject that includes at least one of a belief decay rate and a learning rate, and the predefined model is applied to the learning variable(s) to classify an expected cause of an individual bias of the mammalian subject toward or away from active-escape behaviour.