Active Humidification Device with Flow-Synchronized Nebulizer

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Solution Overview

Problem

Existing patient breathing circuit humidification systems fail to maintain optimal air temperature and humidity levels, as passive humidifiers only reflect exhaled heat and moisture, while active systems are needed to achieve desired inhalation conditions of 37°C and 44mg/l.

Innovation Solution

An active humidification device with a housing, air conditioning chamber, heater, temperature and humidity sensor, air flow sensor, and a humidity generator controlled by a controller to regulate humidity and temperature, featuring an electro-resistive heater and a piezo electric mesh nebulizer to deliver precise humidity levels during inhalation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If a passive humidifier (HME or sedation device) is used in the patient breathing circuit, then the device structure is simple and requires no active power, but it cannot maintain optimal air temperature and humidity levels (only reflects exhaled heat and moisture at approximately 32°C and 33mg/l, below the desired 37°C and 44mg/l)

Engineering Contradiction:
Improveair temperatureVSAvoiddevice complexity
Core Design Contradiction:
TemperatureVSDevice complexity

Solution Approach 1:

The patent combines multiple functions into a single integrated housing: the air conditioning chamber, heater, humidity generator, and sensors are merged into one device that interfaces with the breathing circuit. This integration achieves optimal temperature and humidity control (37°C and 44mg/l) while managing system complexity through unified design.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The housing serves multiple functions simultaneously: it acts as a structural enclosure, an air conditioning chamber for temperature control, a mounting platform for the heater and humidity generator, and a housing for sensors. This multi-functionality enables comprehensive environmental control while avoiding the need for separate devices.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If an active humidification device is used to achieve optimal air conditions (37°C and 44mg/l), then the air temperature and humidity can be maintained at desired levels, but the device complexity increases with multiple components including heater, humidity generator, and sensors

Engineering Contradiction:
Improvehumidity control reliabilityVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent incorporates temperature and humidity sensors that continuously monitor the air conditions within the air conditioning chamber. These sensors provide feedback to the control system, which automatically adjusts the heater and humidity generator to maintain reliable optimal conditions (37°C and 44mg/l), ensuring consistent performance despite the increased device complexity.

Inventive Principle:
Principle #23Feedback

3Reliability

If the nebulizer operates continuously to maintain humidity, then the desired humidity level can be maintained, but the nebulizer may become clogged and operational reliability decreases

Engineering Contradiction:
Improvenebulizer operational reliabilityVSAvoidhumidity generation efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent employs an air flow sensor to detect patient inhalation and triggers the nebulizer to operate only during inhalation phases. This periodic operation synchronized with patient breathing maintains the required humidity levels while preventing continuous operation that would lead to clogging, thereby improving nebulizer reliability and operational efficiency.

Inventive Principle:
Principle #19Periodic action

4Power

If the heater element is exposed directly to the air conditioning chamber, then heating efficiency is maximized, but the housing may overheat and create harmful thermal effects on the patient

Engineering Contradiction:
Improveheating efficiencyVSAvoidthermal harm to patient
Core Design Contradiction:
PowerVSObject-affected harmful factors

Solution Approach 1:

The patent introduces an insulating layer as an intermediary between the heater element and the housing. This insulating layer allows the heater to operate at high power for efficient heating while preventing excessive heat transfer to the housing and patient interface, thereby eliminating thermal harm while maintaining heating efficiency.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device effectively maintains air at pre-set temperature and humidity levels, ensuring optimal breathing conditions for patients by synchronizing nebulizer operation with inhalation and adjusting moisture output based on air flow rate, preventing clogging and maintaining desired humidity and temperature.

Implementation Method 1

a heater mounted within the air conditioning chamber... the heater comprises an electro-resistive heater element

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 2

the humidity generator comprises a piezo electric mesh nebulizer

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Data Source

PatentEP4260893B1Active humidification device
Publication Date: 2024.10.30 SEDANA MEDICAL LTD
  • EP4260893B1 patent drawingFigure 1
  • EP4260893B1 patent drawingFigure 2
  • EP4260893B1 patent drawingFigure 3

AI summary

An active humidification device (1) is for mounting in a patient breathing circuit, which typically includes a ventilator connected by a Y-piece with an elongate patient breathing tube for a patient, a sedation device may be mounted in the patient breathing tube between the ventilator and the patient to passively reflect heat and moisture to the patient as the patient breathes. The active humidification device (1) of this invention is mounted in the patient breathing tube between the sedation device and the patient, and is operable to maintain breathing air delivered to the patient at a pre-set desired temperature and humidity. The active humidification device (1) comprises a housing (11) having an air conditioning chamber (12) extending through the housing (11) between a first connector port (14), for connection via the patient breathing tube with the ventilator, and a second connector port (15), for connection via the patient breathing tube with the patient in use. A heater (16) is mounted within the air conditioning chamber (12) and a temperature and humidity sensor (17) is mounted at a top of the air conditioning chamber (12). Also mounted within the air conditioning chamber (12) is an air flow sensor (18) which is operable to measure air flow rate and the direction of air flowing through the air conditioning chamber (12). A humidity generator such as a nebuliser (20) is mounted on the housing (11) and has a water vapour outlet communicating with the air conditioning chamber (12). A controller (22) is operably connected to the heater (16), the temperature and humidity sensor (17), the air flow sensor (18) and the nebuliser (20) for controlling operation of the active humidification device (1) to maintain air delivered from the active humidification device (1) to the patient in use at the pre-set desired temperature and relative humidity.