Acute Non-Excitatory Cardiac Therapy With Adaptive Electrical Control
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Solution Overview
Problem
Existing electrical heart failure therapies are inadequate for providing acute, non-excitatory treatment to patients with conditions such as angina, myocardial infarction, heart surgery recovery, heart failure, or those requiring improved blood flow and stress relief.
Innovation Solution
A system comprising an implantable controller that receives indications of patient conditions and provides non-excitatory electrical heart failure therapy, adjusting parameters like pulse amplitude, width, and frequency based on patient needs, including sensors for detection and external inputs.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If non-excitatory electrical therapy is applied to increase cardiac contractility, then cardiac function is improved, but the risk of inadequate acute treatment response increases
Solution Approach 1:
The system dynamically adjusts electrical therapy parameters (amplitude, width, frequency) based on real-time detection of cardiac conditions and response monitoring, transitioning from static to adaptive treatment to optimize efficacy while managing complexity
Solution Approach 2:
The system incorporates feedback mechanisms where sensors monitor cardiac response to electrical therapy and automatically adjust treatment parameters, creating a closed-loop control system that improves reliability while managing complexity through automation
2Reliability
If electrical therapy parameters are increased to treat acute heart conditions, then treatment efficacy is improved, but the risk of adverse effects increases
Solution Approach 1:
The system uses dynamic parameter adjustment where amplitude, width, and frequency are continuously optimized based on detected cardiac conditions and treatment response, preventing both under-treatment and over-stimulation
Solution Approach 2:
The system changes electrical therapy parameters (amplitude, width, frequency) based on detected cardiac conditions and treatment response, allowing optimization of efficacy while staying within safe operational boundaries
3Measurement precision
If personalized electrical therapy is provided based on patient detection, then treatment precision is improved, but device complexity increases
Solution Approach 1:
The implantable device performs multiple functions including sensing cardiac conditions, delivering electrical therapy, and monitoring treatment response, consolidating what could be separate systems into one integrated solution
Solution Approach 2:
The system automatically detects cardiac conditions and adjusts therapy parameters without requiring external intervention, making the device self-regulating and reducing the need for complex external control systems
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively treats acute heart conditions by increasing cardiac contractility, improving blood flow, and alleviating stress through personalized electrical therapy adjustments.
Implementation Method 1
providing an effective amount of non-excitatory electrical heart failure therapy
Data Source
AI summary
An aspect of some embodiments of the invention relates to providing acute non-excitatory electrical heart failure therapy to a patient according to one or more criteria. Exemplary criteria are one or more of suffering from an acute angina episode, a patient after a myocardial infraction episode, a patient after heart surgery, a patient that is already on a Cath-Lab and would be beneficial to see if the treatment could help the patient, patients that suffer from heart failure and optionally already receive chronic non-excitatory electrical heart failure therapy, a patient that requires an improvement in blood flow, patients that show positive results from trial activation of acute non-excitatory electrical heart failure therapy, patients that require assistance in performing daily activities, like exercise, social events, after taking certain drugs, performing intercourse, sleeping and suffer from emotional stress.


