Acylhydrazone Bleaching with Protease for Low-Temperature Stain Removal

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Solution Overview

Problem

Conventional bleaching agents based on active oxygen exhibit limited performance at low temperatures, and increasing bleaching agent concentrations can reduce the effectiveness of enzymes like protease and lipase, leading to reduced stain removal efficiency.

Innovation Solution

The use of specific proteases with defined amino acid sequences, such as those with 98.5% identity to SEQ ID NO:1 or 70-99% identity to SEQ ID NO:2, in combination with acylhydrazones, enhances bleaching performance even at low temperatures by improving the removal of protein and fat-containing stains.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the amount of bleach is increased to improve bleaching performance, then bleaching efficiency is improved, but the performance of enzymes such as protease and lipase is reduced

Engineering Contradiction:
Improvebleaching efficiencyVSAvoidenzyme performance
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent introduces acylhydrazones as intermediary compounds that facilitate bleaching at lower temperatures without requiring high concentrations of bleach. These compounds act as mediators between the bleaching agent and the substrate, enabling effective bleaching while preserving enzyme activity by reducing the need for harsh bleaching conditions

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the temperature parameter by optimizing formulations for low-temperature washing (30°C or lower). By modifying the chemical parameters through the use of acylhydrazones and specific protease-lipase combinations, the system achieves effective bleaching and stain removal at temperatures where conventional high-bleach formulations would be ineffective or damaging to enzymes

Inventive Principle:
Principle #35Parameter changes

2Use of energy by moving object

If washing temperature is lowered to save energy, then energy consumption is reduced, but bleaching performance is limited

Engineering Contradiction:
Improveenergy consumptionVSAvoidbleaching performance
Core Design Contradiction:
Use of energy by moving objectVSProductivity

Solution Approach 1:

The patent fundamentally changes the temperature parameter by developing formulations specifically optimized for low-temperature operation (30°C or lower). The chemical composition is modified to include acylhydrazones and specific enzyme combinations that maintain high bleaching and stain removal performance at these reduced temperatures, eliminating the need for high-temperature processing

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite formulation system combining acylhydrazones with specific protease and lipase enzymes. This composite material works synergistically to provide both bleaching and stain removal functions at low temperatures, where neither component would be fully effective alone. The composite formulation overcomes the limitations of conventional single-component systems

Inventive Principle:
Principle #40Composite materials

3Use of energy by moving object

If conventional bleaching agents are used at low temperatures, then energy consumption is reduced, but bleaching performance remains limited

Engineering Contradiction:
Improveenergy consumptionVSAvoidbleaching performance
Core Design Contradiction:
Use of energy by moving objectVSProductivity

Solution Approach 1:

The patent changes the chemical parameters of the bleaching system by introducing acylhydrazones that are specifically effective at low temperatures. This parameter change allows the system to maintain high bleaching performance at 30°C or lower, whereas conventional bleaching agents would require higher temperatures to achieve similar results

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a simplified version of high-temperature bleaching performance that works at low temperatures. By using acylhydrazones as a substitute for high-temperature activation, the system copies the effective bleaching outcome without requiring the high-temperature condition, thereby reducing energy consumption while maintaining performance

Inventive Principle:
Principle #26Copying

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combined use of these proteases and acylhydrazones significantly enhances bleaching performance, particularly at low temperatures, resulting in improved stain removal and increased bleaching efficiency compared to using either component alone.

Implementation Method 1

Proteases are enzymes that catalyze the hydrolysis of amide bonds in protein substrates

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Implementation Method 2

The bleach-enhancing effect of acylhydrazones is known from international patent applications

Methodology Applied
Scientific EffectCatalysis: Catalysis

Implementation Method 3

Conventional active oxygen-based bleaching agents perform well at application temperatures of 40°C and above

Methodology Applied
Scientific EffectOxidation: Oxidation

Data Source

PatentEP3143115B2Washing and cleaning agent with enhanced bleaching performance
Publication Date: 2024.08.14 HENKEL KGAA
  • EP3143115B2 patent drawing
  • EP3143115B2 patent drawing
  • EP3143115B2 patent drawing

AI summary

The problem addressed by the invention is that of improving the bleaching power of acylhydrazones in detergents and cleaning agents that contain peroxygen. This was achieved through the use of a protease.