AD Nutritional Composition for Digestibility and Cognitive Support
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Solution Overview
Problem
There is a lack of nutritional compositions specifically targeted at individuals with Alzheimer's disease or those at high risk, which are easy to digest and absorb, and can help improve physical function to delay the onset and progression of Alzheimer's disease.
Innovation Solution
A nutritional composition comprising specific ratios of proteinaceous substances, fatty substances, carbohydrates, dietary fibers, trace and major minerals, vitamins, taurine, and lactoferrin, including whey protein, soy protein, rapeseed oil, galactooligosaccharides, and various vitamins, which are mixed and stirred to create a formulation that is easy to digest and absorb, providing essential nutrients for individuals with Alzheimer's disease or high-risk groups.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If general nutritional compositions are used for Alzheimer's disease patients, then basic nutritional needs are met, but the composition is not optimized for AD-specific physiological requirements and digestibility
Solution Approach 1:
The patent applies local quality by tailoring the nutritional composition specifically to the physiological needs of Alzheimer's disease patients. The formula includes optimized ratios of protein (16-24%), fat (20-30%), and carbohydrates (50-65%), along with specific amounts of vitamins, minerals, and antioxidants that address AD-related metabolic changes, cognitive decline, and increased oxidative stress, rather than using generic nutritional formulations.
Solution Approach 2:
The patent implements parameter changes by adjusting key nutritional parameters to suit AD patients' requirements. This includes modifying the protein-to-carbohydrate ratio, increasing antioxidants (vitamin E: 10-50 mg, vitamin C: 50-200 mg), adding specific fatty acids (omega-3: 500-2000 mg), and controlling portion sizes (400-800 kcal per serving) to address the unique metabolic and cognitive needs of this population.
2Reliability
If complex nutritional formulations are developed for AD patients, then nutritional effectiveness is improved, but ease of manufacture and preparation becomes more difficult
Solution Approach 1:
The patent applies segmentation by dividing the complex nutritional formulation into distinct functional components: macronutrients (proteins from whey/soy/casein, fats from fish oil/olive oil/coconut oil, carbohydrates from oats/rice), micronutrients (vitamins A, C, E, B complex; minerals like zinc, magnesium, calcium), and bioactive compounds (antioxidants, omega-3 fatty acids, fiber). This modular structure facilitates standardized manufacturing while maintaining therapeutic effectiveness.
Solution Approach 2:
The patent uses composite materials by combining multiple food ingredients with complementary nutritional profiles into a unified formulation. The composition integrates animal and plant proteins, saturated and unsaturated fats, simple and complex carbohydrates, along with vitamin-mineral complexes and phytochemicals, creating a synergistic nutritional matrix that addresses multiple AD-related deficiencies simultaneously.
3Reliability
If high-quality proteins and fats are included for cognitive function, then physical function improvement is enhanced, but digestibility and absorption may be compromised for elderly patients
Solution Approach 1:
The patent applies parameter changes by selecting protein sources with high digestibility coefficients (whey protein, soy protein, casein) and fats with appropriate fatty acid profiles (omega-3 from fish oil, monounsaturated from olive oil, medium-chain from coconut oil). The formulation adjusts the protein content to 16-24% and fat content to 20-30%, with specific emphasis on easily absorbable forms that meet the reduced digestive capacity of elderly AD patients while maintaining anabolic and cognitive benefits.
Data Source
AI summary
A nutritional composition for an Alzheimer's disease population or a high-risk population, prepared from the following raw materials in parts by weight: 170-300 parts of proteinaceous substances, 85-250 parts of fatty substances, 450-770 parts of carbohydrates, 10-155 parts of dietary fiber substances, 1.2-3.5 parts of trace minerals, 47-180 parts of macro minerals, 2.0-8.3 parts of vitamins, 0.1-1.0 parts of taurine, 0.05-0.5 parts of L-carnitine, and 0.9-1.0 parts of lactoferrin. The composition is rich in high-quality animal and plant proteins, fatty acids, various vitamins, minerals, and water-soluble dietary fibers, has remarkable effects in slowing down the occurrence and development of Alzheimer's disease, and is suitable for an Alzheimer's disease population or a high-risk population to eat.