Adaptive Alert Classifier for Clinical Episode Filtering

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Solution Overview

Problem

Clinical staff are overwhelmed by repetitive alerts from a small percentage of patients, necessitating a method to automatically identify new or different clinical episodes to filter out non-significant alerts and prioritize attention on actual changes.

Innovation Solution

An adaptive alert classifier uses unsupervised training to identify characteristics of significant clinical episodes, grouping past episode vectors into clusters using algorithms like k-means, and issuing alerts for new episodes not assigned to these clusters or deemed clinically significant, with newer episodes weighted more heavily in re-computation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If alerts are generated for all clinical episodes, then comprehensive monitoring is achieved, but alert fatigue and resource overload occur

Engineering Contradiction:
Improvecomprehensive monitoringVSAvoidalert review workload
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent segments alerts into two categories: standard alerts for episodes matching existing clusters, and potential alerts for episodes forming new clusters. This segmentation allows clinical staff to prioritize potential alerts while automatically handling standard alerts through the system, reducing overall workload while maintaining comprehensive monitoring.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces an intermediary clustering algorithm that acts as a filter between episode detection and alert generation. This intermediary automatically processes and groups episodes, generating potential alerts only when new patterns are detected, thereby reducing the volume of alerts requiring human review while preserving important cases.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If all episodes are reviewed by clinical staff, then no significant episodes are missed, but time and resources are wasted on repetitive alerts

Engineering Contradiction:
Improveepisode detection accuracyVSAvoidreview time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent performs preliminary clustering analysis automatically before presenting alerts to clinical staff. By pre-processing episodes through unsupervised learning algorithms, the system identifies and groups similar episodes, flagging only novel or significant cases for human review. This preliminary action ensures no significant episodes are missed while dramatically reducing the time required for manual review.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system enables self-service monitoring by automatically detecting, clustering, and evaluating episodes using machine learning algorithms. The clustering model independently processes episodes, generating potential alerts only when novel patterns are detected, thereby eliminating the need for staff to review every episode while maintaining high detection accuracy.

Inventive Principle:
Principle #25Self-service

3Quantity of substance

If clustering algorithms group all episodes equally, then historical data is utilized, but recent significant episodes may be obscured by older data

Engineering Contradiction:
Improvedata utilizationVSAvoidepisode significance detection
Core Design Contradiction:
Quantity of substanceVSMeasurement precision

Solution Approach 1:

The patent applies local quality by assigning different weights to episodes based on their recency. More recent episodes receive higher weights in the clustering calculation, while older episodes receive lower weights. This weighted approach ensures that recent significant episodes are not obscured by historical data, while still utilizing the broader dataset for pattern recognition.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent implements dynamic weighting in the clustering algorithm, where the influence of each episode on cluster formation changes over time. Recent episodes have greater dynamic influence on cluster centroids and membership assignments, allowing the system to adapt to changing patient conditions and prioritize detection of recent significant episodes while maintaining historical context.

Inventive Principle:
Principle #15Dynamics

Data Source

PatentEP3721445B1System to improve clinical workflow
Publication Date: 2024.04.10 CARDIAC PACEMAKERS INC
  • EP3721445B1 patent drawingFigure 1
  • EP3721445B1 patent drawingFigure 2
  • EP3721445B1 patent drawingFigure 3

AI summary

Described herein are systems and methods for classifying clinical episodes in order to more accurately generate alerts for those episodes that warrant them. In some embodiments, alerts are only generated for those episodes that are new or different from previous episodes, where the previous episodes have been found to be not significant enough to warrant an alert.