Adaptive Atomizer for Variable Particle Size Aerosols

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Solution Overview

Problem

Current atomizers are limited in producing pharmaceutical aerosols of specific particle sizes, failing to adapt to individual patient body states, treatment medicines, and other factors, which hinders precise treatment as different tissues in the respiratory system require varying particle sizes for effective absorption.

Innovation Solution

An atomizer comprising a sensor module, waveform pattern determination module, high-frequency oscillation circuit, signal modulation module, piezoelectric device, and porous screen, dynamically generating pharmaceutical aerosols with varying particle sizes based on patient body states, treatment medicine types, and other factors through modulation control signals and vibration signals.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a single atomizer produces pharmaceutical aerosols of a specific particle size, then the device structure is simple and easy to manufacture, but it cannot meet the diverse therapeutic needs of different patients and tissues

Engineering Contradiction:
Improveadaptability to different patients and tissuesVSAvoiddevice structure complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The atomizer employs a piezoelectric device that can dynamically adjust its vibration frequency and amplitude based on real-time patient feedback from the sensor module. This dynamic adjustment capability allows a single device to produce aerosols of different particle sizes adaptively, resolving the contradiction between versatility and complexity by making the device parameters changeable rather than fixed

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system incorporates a sensor module that detects patient response and feeds this information back to the control unit, which then adjusts the piezoelectric device parameters accordingly. This feedback mechanism enables the atomizer to adapt to individual patient needs and tissue requirements, achieving versatility through intelligent control rather than multiple fixed devices

Inventive Principle:
Principle #23Feedback

2Adaptability or versatility

If multiple atomizers are used to produce pharmaceutical aerosols of different particle sizes, then various therapeutic needs can be met, but the device complexity and number of components increase

Engineering Contradiction:
Improveability to meet various therapeutic needsVSAvoidnumber of atomizers required
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The invention creates a universal atomizer that can perform multiple functions by dynamically adjusting its operating parameters. The piezoelectric device can generate vibrations at different frequencies and amplitudes, enabling a single device to produce aerosols suitable for different respiratory tract targets (upper respiratory tract, lower respiratory tract, alveolar region, lung parenchyma), thereby replacing the need for multiple specialized atomizers

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system changes the physical parameters of aerosol generation by adjusting the vibration frequency and amplitude of the piezoelectric device. By varying these parameters, the atomizer can control the particle size distribution of the pharmaceutical aerosols to match different therapeutic requirements, achieving multi-functionality through parameter modulation rather than through multiple devices

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If pharmaceutical aerosols of fixed particle size are used, then the atomization process is simple and stable, but precision treatment cannot be achieved for different patients and conditions

Engineering Contradiction:
Improveprecision treatment capabilityVSAvoidatomization process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The atomization process is made dynamic through the piezoelectric device that can adjust its vibration characteristics in real-time. This allows the system to optimize aerosol particle size for each specific patient and treatment condition, achieving precision treatment by adapting the atomization parameters rather than using fixed, simple processes

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The sensor module provides real-time feedback on patient response and physiological state, which the control unit uses to adjust the atomization parameters. This feedback loop enables precision treatment by continuously optimizing the aerosol particle size based on actual patient needs, transforming a simple fixed process into an intelligent adaptive process

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precision treatment by adaptively adjusting particle sizes of pharmaceutical aerosols to match specific tissues, ensuring effective absorption and treatment outcomes.

Implementation Method 1

a piezoelectric device, electrically connected to the signal modulation module, configured to vibrate according to the vibration signal

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Data Source

PatentUS20230372638A1Atomizer and atomization method for adaptively generating pharmaceutical aerosols of different particle sizes
Publication Date: 2023.11.23 NATIONAL TSING HUA UNIVERSITY
  • US20230372638A1 patent drawing
  • US20230372638A1 patent drawing
  • US20230372638A1 patent drawing

AI summary

An atomizer for adaptively generating pharmaceutical aerosols of different particle sizes is illustrated, which comprises a sensor module, a waveform pattern determination module, a high-frequency oscillation circuit, a signal modulation module, a piezoelectric device and a porous screen. The sensor module senses a body state of the patient, wherein the body state includes a breathing state. The waveform pattern determination module generates a modulation control signal according to the body state. The high-frequency oscillation circuit provides a high-frequency oscillation signal. The signal modulation module modulates the high-frequency oscillation signal by using the modulation control signal to generate a vibration signal. The piezoelectric device vibrates according to the vibration signal. According to vibration of the piezoelectric device, the porous screen presses the liquid medicine through a plurality of holes of the porous screen to generate a plurality of pharmaceutical aerosols.