Adaptive Bandwidth Quantitative Ultrasound for Deep Tissue Imaging

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Solution Overview

Problem

Current quantitative ultrasound (QUS) methods face limitations in accurately characterizing biological and non-biological materials due to noise interference and attenuation, which affect the signal-to-noise ratio (SNR) as ultrasound signals travel deeper, leading to reduced accuracy in material typing and imaging.

Innovation Solution

The integration of adaptive-bandwidth methods that adjust the spectral content computation based on the signal-to-noise ratio (SNR), combining statistics of envelope detected echo signals with normalized power spectra and global variables, enhances the accuracy of QUS results by focusing on noise-free data for classification and imaging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If QUS methods use fixed bandwidth spectral analysis, then processing is simple, but accuracy decreases due to noise interference at deeper depths

Engineering Contradiction:
ImproveQUS estimation accuracyVSAvoidsignal processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements adaptive bandwidth spectral analysis where the bandwidth is dynamically adjusted based on the signal-to-noise ratio (SNR) at different depths. The system automatically selects optimal bandwidth parameters for each depth region, transitioning from fixed to dynamic processing to maintain accuracy while managing complexity through automated adaptation.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes the spectral analysis bandwidth parameter adaptively based on SNR conditions. By modifying the bandwidth parameter according to signal quality at different depths, the system optimizes measurement precision without requiring manual intervention, resolving the contradiction between simplicity and accuracy.

Inventive Principle:
Principle #35Parameter changes

2Loss of information

If QUS analysis includes all frequency bandwidth, then data utilization is maximized, but noise interference increases reducing SNR

Engineering Contradiction:
Improvesignal information utilizationVSAvoidnoise interference
Core Design Contradiction:
Loss of informationVSObject-affected harmful factors

Solution Approach 1:

The patent applies different bandwidth filtering characteristics to different frequency regions and depth regions based on local SNR conditions. Rather than uniform processing, the system tailors the spectral analysis bandwidth to local signal quality, preserving useful information while rejecting noise in specific frequency-depth regions.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The system dynamically changes the effective bandwidth parameter based on measured SNR, allowing optimal utilization of signal information at each depth while automatically excluding frequency ranges dominated by noise, thus balancing information retention with noise rejection.

Inventive Principle:
Principle #35Parameter changes

3Length of stationary object

If ultrasound signals are used for deep tissue imaging, then imaging depth increases, but signal attenuation reduces SNR

Engineering Contradiction:
Improveimaging depthVSAvoidmaterial typing accuracy
Core Design Contradiction:
Length of stationary objectVSMeasurement precision

Solution Approach 1:

The patent implements depth-adaptive spectral analysis where the bandwidth parameter dynamically adjusts with depth. At shallow depths with high SNR, wider bandwidth is used for maximum information extraction. At greater depths where attenuation reduces SNR, the bandwidth automatically narrows to preserve measurement accuracy, enabling reliable deep tissue imaging.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach significantly improves the accuracy of material classification and imaging by eliminating noise interference and adapting to varying SNR conditions, resulting in more precise characterization and localization of materials, such as cancerous tissues and non-biological structures.

Implementation Method 1

echo signals result from spatial variations in the acoustical impedance of the material

Methodology Applied
Scientific EffectAcoustic impedance variation: Acoustics

Implementation Method 2

backscattered from biological or non-biological materials

Methodology Applied
Scientific EffectBackscattering: Scattering

Implementation Method 3

statistics of the envelope of linearly amplified, radio-frequency ultrasound echo signals

Methodology Applied
Scientific EffectEnvelope detection: Homodyne Detection

Implementation Method 4

estimates based on variables of normalized power spectra of linearly amplified, radio-frequency ultrasound echo signals

Methodology Applied
Scientific EffectSpectral analysis:

Data Source

PatentUS10338033B2Typing and imaging of biological and non-biological materials using quantitative ultrasound
Publication Date: 2019.07.02 RIVERSIDE RES INST
  • US10338033B2 patent drawing
  • US10338033B2 patent drawing
  • US10338033B2 patent drawing

AI summary

An ultrasonic material-evaluation or classification method using spectral and envelope-statistics variables from backscattered ultrasound echo signals using an adaptive-bandwidth and combined with global variables. This classification method can be applied to any organ or tissue among biological materials and any non-biological material that produces backscattered signals as a result of microscopic internal in homogeneities such as a crystalline structure.