Adaptive Cell Image Analysis for Abnormal Sample Smears

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Solution Overview

Problem

Cell image analysis devices are limited to processing samples in a single assigned analysis mode, failing to adapt to abnormalities detected during processing, which can affect test accuracy and efficiency.

Innovation Solution

The device automatically switches to an additional analysis mode that matches the detected abnormality, allowing for further processing of the sample smear to improve accuracy and efficiency by capturing and analyzing cell images under different modes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If the cell image analysis device processes samples only in an assigned analysis mode, then the device complexity is reduced and operation is simplified, but the adaptability to different abnormalities and test accuracy deteriorate

Engineering Contradiction:
Improveadaptability to abnormalitiesVSAvoiddevice complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The analysis mode is changed from static (fixed assigned mode) to dynamic (automatically switchable between assigned and additional modes). The control device dynamically selects and switches between analysis modes based on abnormality detection results, allowing the system to adapt to different sample conditions while maintaining a relatively simple fixed hardware structure.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The cell image analysis device is enhanced to perform multiple analysis functions by automatically adding additional analysis modes based on detected abnormalities. The same imaging and analysis hardware can now handle both the originally assigned analysis mode and additional specialized analysis modes, making the device universally applicable to various abnormality types without requiring separate dedicated devices for each function.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If the device automatically adds and switches to additional analysis modes, then the test accuracy and efficiency are improved, but the processing time and operational complexity increase

Engineering Contradiction:
Improvetest accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The device performs preliminary detection in the assigned analysis mode to identify abnormalities before initiating additional analysis modes. This preliminary action allows the system to determine whether additional analysis is needed, avoiding unnecessary processing time for normal samples while ensuring thorough analysis for abnormal cases.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system uses feedback from the initial analysis results to automatically determine whether to add and switch to additional analysis modes. The control device receives feedback about detected abnormalities and dynamically adjusts the analysis process accordingly, ensuring that additional analysis is performed only when necessary to maintain accuracy while minimizing unnecessary processing time.

Inventive Principle:
Principle #23Feedback

3Reliability

If the device processes samples in multiple analysis modes, then the comprehensiveness of sample examination is improved, but the productivity per unit time decreases

Engineering Contradiction:
Improvecomprehensiveness of examinationVSAvoidprocessing efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The device applies partial action by performing additional analysis modes only for samples that exhibit specific abnormalities, rather than applying all analysis modes to every sample. This selective approach ensures comprehensive examination of abnormal samples while maintaining high processing efficiency for normal samples, optimizing the balance between reliability and productivity.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The system automatically determines and executes additional analysis modes without requiring manual intervention or reconfiguration. The control device self-manages the analysis process by detecting abnormalities and autonomously switching to appropriate additional analysis modes, maintaining high productivity while ensuring comprehensive examination when needed.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS12455223B2Cell image analysis device and sample analysis method
Publication Date: 2025.10.28 SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
  • US12455223B2 patent drawing
  • US12455223B2 patent drawing
  • US12455223B2 patent drawing

AI summary

Provided are cell image analysis devices and sample analysis methods. A sample smear of a test sample is imaged by an imaging device in an assigned analysis mode to obtain first cell images of the test sample, which are identified and analyzed by a control device. If it is identified that there is preset abnormality in the sample smear, an analysis mode different from the assigned analysis mode and corresponding to the present abnormality is determined as an additional analysis mode, and the imaging device is controlled to image the sample smear in the additional analysis mode. The additional analysis mode matches with the preset abnormality, so that the imaging device is allowed to obtain cell images in the additional analysis mode, to identify and analyze the cell images matching the preset abnormality, thereby increasing processing efficiency and accuracy of processing result.