Adaptive Radiation Therapy Planning via Parallel Image Processing

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Solution Overview

Problem

Conventional radiation therapy plans fail to adapt to anatomical changes in tumors during treatment, risking healthy tissues due to inaccurate dose delivery, and require rapid re-planning to maintain therapy efficacy.

Innovation Solution

A system and method for generating adaptive radiation therapy plans by parallel processing of image registration, ROI determination, and dose distribution analysis using processors to rapidly update treatment plans based on sequential scans, allowing for real-time adjustments to anatomical changes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a conventional radiation therapy plan is used without adaptation, then the treatment plan can be generated quickly, but the accuracy of dose delivery deteriorates due to anatomical changes in the tumor

Engineering Contradiction:
Improvedose delivery accuracyVSAvoidre-planning time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The system dynamically updates the radiation therapy plan by comparing sequential images to detect anatomical changes in the tumor. When changes are detected, the treatment plan is automatically adjusted to maintain dose delivery accuracy, transforming the static conventional approach into a dynamic adaptive system that responds to real-time anatomical variations

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system implements a feedback mechanism where sequential images are acquired during treatment, compared to detect anatomical changes, and used to trigger plan adaptation when necessary. This closed-loop feedback ensures dose delivery accuracy is maintained by continuously monitoring and adjusting the treatment plan based on actual tumor anatomy

Inventive Principle:
Principle #23Feedback

2Manufacturing precision

If a re-planning procedure is performed to adapt to anatomical changes, then the dose delivery accuracy is improved, but the treatment time increases causing delays

Engineering Contradiction:
Improvedose delivery accuracyVSAvoidtreatment delivery speed
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The system performs partial re-planning by only updating portions of the treatment plan that are affected by detected anatomical changes, rather than completely re-planning the entire treatment. This selective approach maintains dose delivery accuracy for affected regions while minimizing overall treatment time and preserving productivity

Inventive Principle:
Principle #16Partial or excessive action

3Adaptability or versatility

If frequent imaging scans are performed to monitor anatomical changes, then the adaptability of the treatment plan is improved, but the complexity of the system increases

Engineering Contradiction:
Improvetreatment plan adaptabilityVSAvoidsystem complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system segments the treatment monitoring process into discrete steps: acquiring sequential images at predetermined intervals, comparing images to detect changes, and triggering plan adaptation only when changes are detected. This segmentation allows frequent monitoring without proportionally increasing system complexity, as the adaptive response is activated only when necessary

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS12350518B2Systems and methods for generating adaptive radiation therapy plan
Publication Date: 2025.07.08 SHANGHAI UNITED IMAGING HEALTHCARE
  • US12350518B2 patent drawing
  • US12350518B2 patent drawing
  • US12350518B2 patent drawing

AI summary

A method may include obtaining a first image related to one or more target objects generated by a first scan. The method may also include obtaining a first radiation therapy plan for treating the one or more target objects. The method may also include obtaining a second image related to the one or more target objects generated by a second scan. The second scan may be performed later than the first scan. The method may also include determining, based on the first radiation therapy plan, the first image, and the second image, a target radiation therapy plan to treat the one or more target objects. The target radiation therapy plan may be the first radiation therapy plan or a second radiation therapy plan associated with the second image, wherein at least a portion of the determining the target radiation therapy plan may be performed in parallel.