Adaptive Therapy Program Selection Based on Patient State
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Solution Overview
Problem
Current medical therapy systems for managing movement disorders and other neurodegenerative impairments lack the ability to dynamically adjust therapy delivery based on the patient's current state, such as movement, sleep, or speech states, leading to suboptimal symptom management.
Innovation Solution
A system and method that determine the patient's state and select a corresponding therapy program from a stored set of programs, adjusting therapy parameter values to provide tailored treatment for movement, sleep, or speech states by using biosignals, volitional inputs, or activity sensors to deliver electrical stimulation or pharmaceuticals effectively.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a single fixed therapy program is delivered continuously, then the device complexity is reduced and ease of operation is improved, but the adaptability to different patient states (movement, sleep, speech) deteriorates and symptom management becomes suboptimal
Solution Approach 1:
The therapy system dynamically adjusts therapy parameters based on detected patient states. The system transitions from static fixed therapy delivery to dynamic state-responsive therapy delivery, where therapy programs are automatically selected and modified based on real-time detection of movement, sleep, or speech states through biosignals and sensor inputs.
Solution Approach 2:
The system changes therapy parameters (frequency, amplitude, pulse width, electrode selection) based on detected patient states. Different parameter sets are applied for movement states versus sleep states versus speech states, allowing optimization of therapy efficacy for each specific state without requiring manual reprogramming.
2Adaptability or versatility
If multiple therapy programs are stored and selected based on patient state, then the adaptability to different patient states is improved, but the device complexity increases
Solution Approach 1:
The therapy system segments the overall therapy delivery into distinct state-specific programs. Each program is optimized for particular patient states (movement, sleep, speech), allowing the complex task of state-responsive therapy to be divided into manageable, pre-configured modules that can be automatically selected based on detected state.
Solution Approach 2:
The system performs self-service by automatically detecting patient states and selecting appropriate therapy programs without requiring manual intervention. The implanted device autonomously monitors biosignals, determines current state, and adjusts therapy parameters accordingly, reducing the burden on patients and clinicians while managing complexity internally.
3Adaptability or versatility
If therapy parameters are continuously adjusted based on real-time state detection, then the adaptability and symptom management are improved, but the energy consumption increases
Solution Approach 1:
The system implements periodic sampling of biosignals and sensor data to detect patient states, rather than continuous monitoring. Therapy parameters are adjusted at discrete intervals based on state transitions, reducing energy consumption while maintaining effective state-responsive therapy delivery.
Data Source
AI summary
A therapy program is selected based on a patient state, where the patient state comprises at least one of a movement state, sleep state or speech state. In this way, therapy delivery is tailored to the patient state, which may include specific patient symptoms. The therapy program is selected from a plurality of stored therapy programs that comprise therapy programs associated with a respective one at least two of the movement, sleep, and speech states. Techniques for determining a patient state include receiving volitional patient input or detecting biosignals generated within the patient's brain. The biosignals are nonsymptomatic and may be incidental to the movement, sleep, and speech states or generated in response to volitional patient input.